ACL_RS07140

Uniprot: A9NEQ4
Description: [cytidine(C)-cytidine(C)-adenosine (A)]-adding enzyme
EC number: 2.7.7.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: A tRNA precursor + 2 CTP + ATP = a tRNA with a 3' CCA end + 3 diphosphate. {ECO:0000256|SAAS:SAAS00415332}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): papS
Gene names (synonym):
Mass: 43,770
Subunit structure [CC]:
Gene ontology (GO): ATP binding [GO:0005524]; nucleotidyltransferase activity [GO:0016779]; RNA binding [GO:0003723]; RNA processing [GO:0006396]
Gene ontology IDs: GO:0003723; GO:0005524; GO:0006396; GO:0016779
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. {ECO:0000256|RuleBase:RU003953, ECO:0000256|SAAS:SAAS00534214}.
Protein families: TRNA nucleotidyltransferase/poly(A) polymerase family
Coiled coil:
Domain [FT]: DOMAIN 20 139 PolyA_pol. {ECO:0000259|Pfam:PF01743}.; DOMAIN 166 225 PolyA_pol_RNAbd. {ECO:0000259|Pfam:PF12627}.; DOMAIN 258 377 tRNA_NucTran2_2. {ECO:0000259|Pfam:PF13735}.
Motif:
Region:
EMBL: CP000896
ProteinModelPortal: A9NEQ4
MEROPS:
EnsemblBacteria KO: ABX80834
UniPathway: K00974
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR032810;IPR002646;IPR032828
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF01743;PF12627;PF13735
SMART:
SUPFAM:
TIGRFAMs:

198837-199986(+)

>nucleotide sequence
ATGAGTTTAAAATCAGCGAAAAATTTAATCAGAGATTTAAAGAAACATGGCTATCAAGCT
TACTTAGTTGGAGGCGTGGTCAGAGACTTTCTAATGAAAGCCAAGTTTAGTGATATCGAT
ATAACTACCAGTGCCAAACCATATGAAGTTATGAAACATTTTAAGGCGGTCCCTACAGGT
ATTAAATATGGTACGATAACTATCATGTATGATAATGTATCCTTTGAAGTGACAACCTTT
AGAACAGATGGTCCTACATCTGACTTTAGACATCCGGATTCCGTCATTTACTCAGATAAC
GTTAATGATGATGTGATGCGTCGTGATTTTACAATGAATGGTATCTTAATGGATGAGTAT
CAAAATATCTATGACTACGTAGGTGGTCAAAGAGATATCGAACATAAAATCATCCGTGCG
ATTGGAGATCCAAACGAACGCTTTAAAGAAGATGCACTACGTATGTTACGAGCATTCTAT
TTCCAATCCAAATTAGGCTTTGAAATAGAACCTGTAACCAAACAAGCAATTCAAGATAAT
GCACATTTAATTAAAGAGTTAGCGATGGAACGCATTCATGCTGAACTCATTAAAATACTT
AAAGGTAAACATCTAAAAACGGCCTTAAACTCCATGATTGAAACAGGTATACATAAAGTA
CTACCTGGATTAGAAAAAGGGATTATACATACCGCTAATTTAGAAGAAATGCCTTTTATT
GATACATTCTTTGCTTTATCATTTACTTTAAACAATGGATTTATTCCGGCTAAATGGACA
TTTTCAAATAGACACCGTCATAAATATCAAAAGGCAAGTGAACTTGCTTTAATGCACCCA
ACAACAATTCCAGATACTGCACTGTATCACTATGGATTAGAGATATCTTTACTTGCTAAT
AAAGTGAACTTTAACTTAGGTAAACAAAGTTATCAAAATCAATCACTTCAAGAAAGATTT
AATAACTTACCACTAAAAAGTGAGTTGGATCTTGCACTGACAAGTCAAGAGATTATGAAT
ATTGTAAATAAAAAAGCCGGTGCTTGGTTAGGTAAATTAAAAGCACACATGATTGATCAT
ATTCTAGAAAAGAAACTGTCTAACAATAAAGAAGCATTAACAAGTTTTGTTAGTACATAT
GAGGTGTAA

>protein sequence
MSLKSAKNLIRDLKKHGYQAYLVGGVVRDFLMKAKFSDIDITTSAKPYEVMKHFKAVPTG
IKYGTITIMYDNVSFEVTTFRTDGPTSDFRHPDSVIYSDNVNDDVMRRDFTMNGILMDEY
QNIYDYVGGQRDIEHKIIRAIGDPNERFKEDALRMLRAFYFQSKLGFEIEPVTKQAIQDN
AHLIKELAMERIHAELIKILKGKHLKTALNSMIETGIHKVLPGLEKGIIHTANLEEMPFI
DTFFALSFTLNNGFIPAKWTFSNRHRHKYQKASELALMHPTTIPDTALYHYGLEISLLAN
KVNFNLGKQSYQNQSLQERFNNLPLKSELDLALTSQEIMNIVNKKAGAWLGKLKAHMIDH
ILEKKLSNNKEALTSFVSTYEV