GCW_00160

Uniprot: A0A0F6CJT5
Description: transketolase
EC number: 2.2.1.1
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate. {ECO:0000256|RuleBase:RU004996}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. {ECO:0000256|RuleBase:RU004996}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): tktA_1
Gene names (synonym):
Mass: 74,160
Subunit structure [CC]: SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU004996}.
Gene ontology (GO): metal ion binding [GO:0046872]; transketolase activity [GO:0004802]; metabolic process [GO:0008152]
Gene ontology IDs: GO:0004802; GO:0008152; GO:0046872
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the transketolase family. {ECO:0000256|RuleBase:RU004996, ECO:0000256|SAAS:SAAS00570687}.
Protein families: Transketolase family
Coiled coil:
Domain [FT]: DOMAIN 12 32 TRANSKETOLASE_1. {ECO:0000259|PROSITE:PS00801}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99357
UniPathway: K00615
CDD:
Gene3D:
HAMAP: 3.40.50.920;3.40.50.970
InterPro:
PANTHER: IPR029061;IPR009014;IPR005475;IPR020826;IPR033247;IPR005474
PIRSF: PTHR11624
PRINTS:
PROSITE:
Pfam: PS00801;PS00802
ProDom: PF02779;PF00456
SMART:
SUPFAM: SM00861
TIGRFAMs: SSF52518;SSF52922

In one protein complex with GCW_00165 GCW_00170 38058-40047(+)

>nucleotide sequence
ATGAACATCCAACAACAAACCATAAACACAATTCGCGTTCTGGGAATTGAGATGATAAAC
AATGCCAAATCTGGACACCCTGGCATGGTTATGTCAGCAGCGCCAATGATGTATGCTTTG
TTTCATGATCACTTAAACTATGATGTTAGCGATCCCAACTATCTTAATCGTGATCGGTTT
ATCTTAAGTGCAGGTCATGGTAGTGCTTTGTTATATGCCACAATGTATGTGGCTGGGTAT
AAGACATTAAGTACAAAGGATTTAAAGAATTTTAGAAAGTTTTCATCTAAAACACCAGGT
CACCCTGAATCAACAATGTTAGCGGGTGTTGATTTTGGTACAGGGCCATTAGGTCAAGGT
GCAGCAACATCTGTTGGTTTTGCGATTGCTGAAGCTAATTTAAGCGCTCGCTTTGATAAG
ATCATTAACCATTATACTTATTGTTTAATTGGTGATGGCGATCTGCAAGAAGGAGTGTGT
CAAGAAGCTTTAGCAGTAGCTGGAAGATATAAGCTTAATAAATTAATCTGACTATATGAT
TCTAATGATGTGCAATTAGATGGTCGGGTAGAAAACTCAACAAATTTTGATGTTGAGATG
TTACTTAAATCTTATCGTTGAAACTACATCTTAATTAAAAATGGTAATGATTATCAAGCG
ATCTCAAATGCGATTGCTCAAGCAAAGAAATCTGATAAACCAACTTTTATTGAAGTTAAA
ACTAAATTAGGTTTTACTAGTTCAGTTGAGAATACAAACAAAGCTCACGGTTCACCTTTT
AGTGATGAAGAGATTAAAAATATTAAGGCTAAGTTTGATTATAAGAACAAACCATTTACA
GTAAGCACTGAGGTTAAAAACCACTTCGAATCAGCGATCTCTCGTGGACTTAAAGCAGCT
GAAGAATTTAATCAACGGTTAGCTAAAGCTAAACCAGAATTAAAAGAAAAATTCATTACC
CAAGTAAAAGAAGAAAAGATTAACTTCCCTAAGAGTTTAATTAACGAATTTAATGTTGAT
CAGTACGATTCAACCCGTAATTTATTTGGGAAGGTGTTCAAAGAACTAACCAAGATTAAT
GACAATATCTTGGTTGTTAATTGTGATCTATCAAGCTCAACAAAAGTGGTCACGCACAAT
AATGCTAGATTTGATCACGGCCATTATCAAAACCAATTTGTTGATGTTGGTGTAAGAGAG
TTCTTAGCAGGGTGTATTGTTAATGGGATTGTGGCTCACAAAGGTTTAAAAGCTGTATCT
TCAACGTTTATGGCTTTTAGTGATTACAACAAACCCGCTCTAAGATTAGGCGCAATTAAC
AAGCTAAGTTCATTATACGTTTATTCGCACGACTCATTTAATGTTGGTGAAGATGGTCCA
ACTCACCAACCAATTGAACAACTTTCAGCACTAAGACTGATCCCAGATGTTTTAGTTTAT
CGCCCAGCTAATTTTTACGAACTTTACATAGCGCTTAAAACTGCTTTTGATAAGAAGAAT
CACAAACCGGTTGTCATCTCAACTTCTAGAAGCGAGTTTGATCTAACCAAGGTTAACCCA
AAAACATTTGATGAGGGCTATTATTACCTAAATAAAACTAAGAGTCCTAAACTAAGATTA
ATCGCAACTGGTTCAGATGCTGGTACGGCTTTAAAGTTAGCAAAAATCTTTAAACAAGAA
GGGATTGATATCGATGTTATCTCTGTAGTTTCATTTAAGAAACTAAAAGAAAAACTGGCT
GATCTTGAAGTTCTTAAAGAATTTAAGAAATACAAAAACATCGTGATTGAATCAGGTGTA
AGTAATATCTGGTTTGAATTTGTTAGTTTAGTAATTGGAGTTAATGATTTTGGCTTATCA
GGTAATCCAAATGAAGTGGCAACTTACTTCAGTATGGATCTAGAATCATTAGTAAAATCA
TTAGCATCAATCTTACATAAGAATTACACACAACAAAAGATCGAAGAATTAATCAAAAAT
GCTAATTAA

>protein sequence
MNIQQQTINTIRVLGIEMINNAKSGHPGMVMSAAPMMYALFHDHLNYDVSDPNYLNRDRF
ILSAGHGSALLYATMYVAGYKTLSTKDLKNFRKFSSKTPGHPESTMLAGVDFGTGPLGQG
AATSVGFAIAEANLSARFDKIINHYTYCLIGDGDLQEGVCQEALAVAGRYKLNKLIWLYD
SNDVQLDGRVENSTNFDVEMLLKSYRWNYILIKNGNDYQAISNAIAQAKKSDKPTFIEVK
TKLGFTSSVENTNKAHGSPFSDEEIKNIKAKFDYKNKPFTVSTEVKNHFESAISRGLKAA
EEFNQRLAKAKPELKEKFITQVKEEKINFPKSLINEFNVDQYDSTRNLFGKVFKELTKIN
DNILVVNCDLSSSTKVVTHNNARFDHGHYQNQFVDVGVREFLAGCIVNGIVAHKGLKAVS
STFMAFSDYNKPALRLGAINKLSSLYVYSHDSFNVGEDGPTHQPIEQLSALRLIPDVLVY
RPANFYELYIALKTAFDKKNHKPVVISTSRSEFDLTKVNPKTFDEGYYYLNKTKSPKLRL
IATGSDAGTALKLAKIFKQEGIDIDVISVVSFKKLKEKLADLEVLKEFKKYKNIVIESGV
SNIWFEFVSLVIGVNDFGLSGNPNEVATYFSMDLESLVKSLASILHKNYTQQKIEELIKN
AN