GCW_00295

Uniprot: A0A0F6CJV7
Description: 50S ribosomal protein L2
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. {ECO:0000256|HAMAP-Rule:MF_01320}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rplB
Gene names (synonym):
Mass: 31,258
Subunit structure [CC]: SUBUNIT: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. {ECO:0000256|HAMAP-Rule:MF_01320}.
Gene ontology (GO): large ribosomal subunit [GO:0015934]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; transferase activity [GO:0016740]; translation [GO:0006412]
Gene ontology IDs: GO:0003735; GO:0006412; GO:0015934; GO:0016740; GO:0019843
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L2P family. {ECO:0000256|HAMAP-Rule:MF_01320}.
Protein families: Ribosomal protein L2P family
Coiled coil:
Domain [FT]: DOMAIN 128 259 Ribosomal_L2_C. {ECO:0000259|SMART:SM01382}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99379
UniPathway: K02886
CDD:
Gene3D:
HAMAP: 2.30.30.30;2.40.50.140;4.10.950.10
InterPro: MF_01320_B
PANTHER: IPR012340;IPR022666;IPR014722;IPR002171;IPR005880;IPR022669;IPR022671;IPR014726;IPR008991
PIRSF: PTHR13691
PRINTS: PIRSF002158
PROSITE:
Pfam: PS00467
ProDom: PF00181;PF03947
SMART:
SUPFAM: SM01383;SM01382
TIGRFAMs: SSF50104;SSF50249
69797-70649(+)

>nucleotide sequence
ATGCCGGTTAAGAAAATCGTAAATCGATCAAACAGTGGGATTCATCACAAGATCTCAATA
GATTACAGCAAAGTGTTAACTACTAACACTCCGCAAAAATCTTTATTAGCTAAGAAAAAG
AAAAATTCTGGTCGTAATAACCAAGGAAAAATCACAGTAAGACACCGCGGTGGTGGTTCA
AAAAGAAAATATCGGATCATTGATTTCAAAAGAAATCTACATGATGACAAGATTGCCTTA
GTTAAATCAATTGAGTATGATCCAAACAGAAGTGCGTTTATCTCATTAATCGCTTATGAA
AATGGTTACCGATCATACATCCTAACTCCACAAGGAATTAAAGTAGGTGATAAGGTAGTT
TCATCTTCTCAAGCAATCGATATTAAAGTAGGTAACTGTATGCCGCTTGAATTCATCCCT
GAAGGGACAATGGTTCACAATATCGAAATGATTCCTGGTAAAGGTGCTCAGATCGCTAGA
AGTGCTGGAGCTTATGCTCAGATCTTAGGTAAAGATGATACAGGTAAATACATCAACCTA
AAATTAGGTTCAAAAGAAGTTAGAAAATTCTTAAAGAACTGTCGTGCTGTTGTTGGGATT
GCTTCAAACGTTGATCACAACTTAGTTCTATTAGGTAAAGCGGGGACAACTAGACACAAA
GGGATTCGTCCAACTGTTCGTGGTTCTGCTATGAACCCTAATGACCACCCACACGGGGGT
GGTGAAGGTCGCAGCCCAGTAGGTCGTGACGCTCCAAGAACACCATGAGGAAAAAGACAC
ATGGGTGTTAAAACAAGAAATAATAAAAAATCATCTACGCAATTAATTATCCGTAGACGT
AACTCTAAATAG

>protein sequence
MPVKKIVNRSNSGIHHKISIDYSKVLTTNTPQKSLLAKKKKNSGRNNQGKITVRHRGGGS
KRKYRIIDFKRNLHDDKIALVKSIEYDPNRSAFISLIAYENGYRSYILTPQGIKVGDKVV
SSSQAIDIKVGNCMPLEFIPEGTMVHNIEMIPGKGAQIARSAGAYAQILGKDDTGKYINL
KLGSKEVRKFLKNCRAVVGIASNVDHNLVLLGKAGTTRHKGIRPTVRGSAMNPNDHPHGG
GEGRSPVGRDAPRTPWGKRHMGVKTRNNKKSSTQLIIRRRNSK