GCW_00340

Uniprot: A0A0F6CJW6
Description: 50S ribosomal protein L5
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. {ECO:0000256|HAMAP-Rule:MF_01333}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rplE
Gene names (synonym):
Mass: 20,797
Subunit structure [CC]: SUBUNIT: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome. {ECO:0000256|HAMAP-Rule:MF_01333}.
Gene ontology (GO): ribosome [GO:0005840]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; tRNA binding [GO:0000049]; translation [GO:0006412]
Gene ontology IDs: GO:0000049; GO:0003735; GO:0005840; GO:0006412; GO:0019843
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L5P family. {ECO:0000256|HAMAP-Rule:MF_01333, ECO:0000256|RuleBase:RU003930}.
Protein families: Ribosomal protein L5P family
Coiled coil:
Domain [FT]: DOMAIN 23 79 Ribosomal_L5. {ECO:0000259|Pfam:PF00281}.; DOMAIN 84 175 Ribosomal_L5_C. {ECO:0000259|Pfam:PF00673}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal: A0A0F6CJW6
MEROPS:
EnsemblBacteria KO: AHB99388
UniPathway: K02931
CDD:
Gene3D:
HAMAP: 3.30.1440.10
InterPro: MF_01333_B
PANTHER: IPR002132;IPR020930;IPR031309;IPR020929;IPR022803;IPR031310
PIRSF:
PRINTS: PIRSF002161
PROSITE:
Pfam: PS00358
ProDom: PF00281;PF00673
SMART:
SUPFAM:
TIGRFAMs: SSF55282
74059-74617(+)

>nucleotide sequence
ATGAATTTAAAAACTAAATATAAGACAAAAATCGTTCCATTATTACAAAAAGAATTTGGC
TTTTCTTCAGTAATGCAAGTTCCTAAGATCGAAAAGATCGTGATCAACATGGGTGTAGGT
GATGCTACTAAAGATGCAAAACTATTAGAATTAGCACAAGCTGAATTGCAAGCAATTAGT
GGACAAAAACCAGTCATTACTAAAGCACACTCTTCAAACGCTTCTTTCAAAATTAGACAA
GGTCAAGCAATTGGTTGTAAAGTAACTCTAAGAGGTGAAAAGATGTGAAACTTTTTAGAA
AAACTAATTAACATTGCCCTACCACGTGTAAGAGACTTCAGAGGTTTATCAAACCGCGCA
TTTGATGCTAGAGGGAATTACACTCTAGGAATTAAAGAGCAGATCATCTTCCCAGAAATT
ATCTATGATAATGTGAAGAAAATTCGTGGATTCGACGTTACGTTAGTAATTTCATCTGAT
AATGCTAAATACAATCACCGTCTTTTATTAGAATTAGGAATGCCTTTAATTAAGACTAAG
GAACACGCAAATGGCTAA

>protein sequence
MNLKTKYKTKIVPLLQKEFGFSSVMQVPKIEKIVINMGVGDATKDAKLLELAQAELQAIS
GQKPVITKAHSSNASFKIRQGQAIGCKVTLRGEKMWNFLEKLINIALPRVRDFRGLSNRA
FDARGNYTLGIKEQIIFPEIIYDNVKKIRGFDVTLVISSDNAKYNHRLLLELGMPLIKTK
EHANG