GCW_00390

Uniprot: A0A0F6CJX6
Description: lactate dehydrogenase
EC number:
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 181 181 Proton acceptor. {ECO:0000256|PIRSR:PIRSR000102-1}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): ldh
Gene names (synonym):
Mass: 35,412
Subunit structure [CC]:
Gene ontology (GO): oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]; carbohydrate metabolic process [GO:0005975]; carboxylic acid metabolic process [GO:0019752]
Gene ontology IDs: GO:0005975; GO:0016616; GO:0019752
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the LDH/MDH superfamily. {ECO:0000256|RuleBase:RU003369}.
Protein families: LDH/MDH superfamily
Coiled coil:
Domain [FT]: DOMAIN 3 147 Ldh_1_N. {ECO:0000259|Pfam:PF00056}.; DOMAIN 152 317 Ldh_1_C. {ECO:0000259|Pfam:PF02866}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal: A0A0F6CJX6
MEROPS:
EnsemblBacteria KO: AHB99398
UniPathway: K00016
CDD:
Gene3D:
HAMAP: 3.40.50.720;3.90.110.10
InterPro:
PANTHER: IPR001557;IPR022383;IPR001236;IPR015955;IPR016040
PIRSF: PTHR11540
PRINTS: PIRSF000102
PROSITE: PR00086
Pfam:
ProDom: PF02866;PF00056
SMART:
SUPFAM:
TIGRFAMs: SSF51735;SSF56327
80385-81357(+)

>nucleotide sequence
ATGAAAAAAATAGCTGTTATCGGATGTGGATTTGTCGGATCTACGTACATTCTTGACCTA
TTACAACAAGGAGTTCAAGCTGATTACTTACTTGTTGATAAAAACACTAATTTAGCTGAT
GGTCACGTAAGAGACTTACGCGACTCTAAATCATTAAAAAGTCATAACGGATCTACATTT
AATGTTGGAACATACGACGATTTAAAAGATGCTGATGTTGTAGCGATTACTGCTTCAATT
CCAACTGTACCAACTGCTGATGGTGAAGTGTTTACTGACCGTCTACAATTAATGACTGCC
AACGTTAAGATTCTTAACGAAATTGCTTTAGAGTTAAAGCGTGTTGGCTTTAAGGGACTA
AGTATTATTCCAACTAACCCATGTGACGTAATGGCTGGTGTTTATCAAAAAGTTACTGGT
TTTGATCCACACAAGATTATTTCTACAGGTTGTCAACTTGAAACGATGAGAACCAGAAAG
ATGATCTCTGAAGCTTTAGGTGTTAATTCTGACTCTGTTGAAGGGTTCGTTGTTGGTGAA
CACGGTTCAGGTGCAATCGTTCCTTGATCAGTATTTAGAGTTGGTAACGTACCAATGAAG
CAACTAATTGCTGAAGGTAAGATTAAAGAAGAATACGTTAAGGACATCTTCCCAAGAGTA
GTTAAAGAAGCATTTGAAATTATTAAGTTTAAAAAAGCTACTTACTTTGGTATTGCTGAA
TCAATGTCATTAATTACTCGAGCATACATTTACAATTTAAATATGGTTTTAGGTGTAGGT
GTTCAATTAGATGATAAGTATGTTGCTTCTGGCATTTACTTCACAGTTCCAGCAGTTGTT
GGCAAGCACGGATGGAAGTTACACTCTAAATTACAATTAAGCCAAGAAGAACAAGCAGCT
TTTGATAAGAGTGCACTTAACATTCAAAAAGTAACTAAAGACGCATTAGACTTAATTGGT
TTTAAAAACTAG

>protein sequence
MKKIAVIGCGFVGSTYILDLLQQGVQADYLLVDKNTNLADGHVRDLRDSKSLKSHNGSTF
NVGTYDDLKDADVVAITASIPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGL
SIIPTNPCDVMAGVYQKVTGFDPHKIISTGCQLETMRTRKMISEALGVNSDSVEGFVVGE
HGSGAIVPWSVFRVGNVPMKQLIAEGKIKEEYVKDIFPRVVKEAFEIIKFKKATYFGIAE
SMSLITRAYIYNLNMVLGVGVQLDDKYVASGIYFTVPAVVGKHGWKLHSKLQLSQEEQAA
FDKSALNIQKVTKDALDLIGFKN