GCW_00830







Uniprot: A0A0F6CK41
Description: 50S ribosomal protein L7/L12
EC number: 
Annotation score: 2 out of 5
Miscellaneous [CC]: 
Protein existence: Inferred from homology
Catalytic activity: 
Cofactor: 
Enzyme regulation: 
Function [CC]: FUNCTION: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. {ECO:0000256|HAMAP-Rule:MF_00368}.
Pathway: 
Active site: 
Binding site: 
Calcium binding: 
DNA binding: 
Metal binding: 
Nucleotide binding: 
Site: 
Gene names (primary): rplL
Gene names (synonym): 
Mass: 12,574
Subunit structure [CC]: SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. {ECO:0000256|HAMAP-Rule:MF_00368}.
Gene ontology (GO): ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]
Gene ontology IDs: GO:0003735; GO:0005840; GO:0006412
Chain: 
Signal peptide: 
Domain [CC]: 
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L7/L12P family. {ECO:0000256|HAMAP-Rule:MF_00368}.
Protein families: Ribosomal protein L7/L12P family
Coiled coil: 
Domain [FT]: DOMAIN 5 51 Ribosomal_L12_N. {ECO:0000259|Pfam:PF16320}.; DOMAIN 56 121 Ribosomal_L12. {ECO:0000259|Pfam:PF00542}.
Motif: 
Region: 
EMBL: CP006916
ProteinModelPortal: 
MEROPS: 
EnsemblBacteria KO: AHB99463
UniPathway: K02935
CDD: 
Gene3D: cd00387
HAMAP: 3.30.1390.10
InterPro: MF_00368
PANTHER: IPR000206;IPR014719;IPR013823;IPR008932
PIRSF: 
PRINTS: 
PROSITE: 
Pfam: 
ProDom: PF00542;PF16320
SMART: PD001326
SUPFAM: 
TIGRFAMs: SSF48300;SSF54736

In one protein complex with GCW_00825 186674-187040(+)

>nucleotide sequence
ATGGCAAAATTAACAAAAGAACAATTTATTGAAAGTCTAAAAGAAATGACTATCGTTGAA
ATCAACGATGTAATTAAAGCAATCGAAGAAGCATTCGGTGTTTCAGCTGCTGCTCCTGTA
GCTGCTGCTGCAGCTGCTCCAGCGGCTGCTGCTCCAACTGAAGCAACAGTTGTTTTAGTA
TCAGCTGGTGATAAGAAAGTTGAAGTTATTAAACTAGTAAGAGAAGTAACTGGTTTAGGT
TTAATGGATGCTAAGAAAGCAGTTGACACTCCTCCTGCAACTATTAAAGAAAATATGAAT
ATTGAAGAAGCTAAAGCATTAAAAGCTAAGTTCGAAGCTGTTGGTGCTAAAGTTGATCTT
AAATAA


>protein sequence
MAKLTKEQFIESLKEMTIVEINDVIKAIEEAFGVSAAAPVAAAAAAPAAAAPTEATVVLV
SAGDKKVEVIKLVREVTGLGLMDAKKAVDTPPATIKENMNIEEAKALKAKFEAVGAKVDL
K






















© Fisunov Lab of Proteomics, 2016.