GCW_01615

Uniprot: A0A0F6CKF3
Description: glycerol-3-phosphate dehydrogenase
EC number: 1.1.1.94
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + NAD(P)(+) = glycerone phosphate + NAD(P)H. {ECO:0000256|RuleBase:RU000439}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 193 193 Proton acceptor. {ECO:0000256|PIRSR:PIRSR000114-1}.
Binding site: BINDING 108 108 Substrate. {ECO:0000256|PIRSR:PIRSR000114-2}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): gpsA
Gene names (synonym):
Mass: 36,687
Subunit structure [CC]:
Gene ontology (GO): glycerol-3-phosphate dehydrogenase complex [GO:0009331]; glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [GO:0047952]; glycerol-3-phosphate dehydrogenase [NAD+] activity [GO:0004367]; glycerol-3-phosphate dehydrogenase [NADP+] activity [GO:0036439]; NAD binding [GO:0051287]; carbohydrate metabolic process [GO:0005975]; glycerol-3-phosphate catabolic process [GO:0046168]
Gene ontology IDs: GO:0004367; GO:0005975; GO:0009331; GO:0036439; GO:0046168; GO:0047952; GO:0051287
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. {ECO:0000256|RuleBase:RU000437, ECO:0000256|SAAS:SAAS00567958}.
Protein families: NAD-dependent glycerol-3-phosphate dehydrogenase family
Coiled coil:
Domain [FT]: DOMAIN 4 161 NAD_Gly3P_dh_N. {ECO:0000259|Pfam:PF01210}.; DOMAIN 186 321 NAD_Gly3P_dh_C. {ECO:0000259|Pfam:PF07479}.
Motif:
Region: REGION 260 261 Substrate binding. {ECO:0000256|PIRSR:PIRSR000114-2}.
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99575
UniPathway: K00057
CDD:
Gene3D:
HAMAP: 1.10.1040.10;3.40.50.720
InterPro:
PANTHER: IPR008927;IPR013328;IPR006168;IPR006109;IPR011128;IPR016040
PIRSF:
PRINTS: PIRSF000114
PROSITE: PR00077
Pfam:
ProDom: PF07479;PF01210
SMART:
SUPFAM:
TIGRFAMs: SSF48179;SSF51735
378584-379574(+)

>nucleotide sequence
ATGAAAACTAAAATTGGTGTCCTTGGTACGGGAGCTTGAGGAACTGCTCTAGCTAGTATC
TTATTAAAAAACGGTCATATCGTAAAGATGTGAGGAATCGATCAAGACGAAATTAATAAC
CTTAAAACAGGTTATAATAATCGTTATTTTGGTCATAAAAAACTAGTTAAATCACCTGAT
CTAGTTTCAAGTGATTTAGCTGCAGTCGTTGATGGTTGTGATTATTTATTATTAGCAATT
CCATCAAAGTTTTTTAATGATGTGTTAGCAAAACTAGCTAACGTACTAAAAGATCGTAAA
GTTAATCTGATTAATGTAGCTAAGGGAATGGACGGTCAAACTAAACAATTTTGATCAGAA
GTGATCAAACAAGCGTTTAGTAAGAATTTGCTATCATTAACATCATTATTAGGACCTTCG
TTTGCTACTGAAGTGTTTGATAATCATCCAACAGTGATTAATGCCGTATCTAATGATATG
ACTAGTTGTAAAAAAGTGTGTGAACTATTTAATAATGACACTTTTCAACTAGTACCATTT
GACAATGAACTATCAGCACAAATGTTTGCTGCAATTAAAAACGTTTGTGCAATCGGGACT
GGGATTGTTTTTGAACAAACAACATCAGCCAACACTAGATCTGCTTTACTAACCAAACTA
TTTAATGAGATGGATCGTTTGTATGAAAGTTTGGCTAAAGATAAATATCGACCAAAAGAT
TGCACCCAACTTAATGGGATCGGTGATTTTATTCTGACTTGTACAAACGATCAATCAAGA
AACTTTAGTTTTGGTAAGTTAGTGGCTAAATACGGAATTAAAAACGCGTTAGAAAAAAAT
ATCAACACCGTTGAAGGTTATCTGGCAGCTAAAACGATGTATGAGATCATTAAGAACAAT
AATTTAGAGTTAAAACTCCTAATCACAATTTATCAGATCTTATATGAAGATCTGGATAAA
TCTTTTCTAGTTAAAAAGTTGATTAATTAA

>protein sequence
MKTKIGVLGTGAWGTALASILLKNGHIVKMWGIDQDEINNLKTGYNNRYFGHKKLVKSPD
LVSSDLAAVVDGCDYLLLAIPSKFFNDVLAKLANVLKDRKVNLINVAKGMDGQTKQFWSE
VIKQAFSKNLLSLTSLLGPSFATEVFDNHPTVINAVSNDMTSCKKVCELFNNDTFQLVPF
DNELSAQMFAAIKNVCAIGTGIVFEQTTSANTRSALLTKLFNEMDRLYESLAKDKYRPKD
CTQLNGIGDFILTCTNDQSRNFSFGKLVAKYGIKNALEKNINTVEGYLAAKTMYEIIKNN
NLELKLLITIYQILYEDLDKSFLVKKLIN