GCW_01875

Uniprot: A0A0F6CKJ6
Description: arginine deiminase
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: L-arginine + H(2)O = L-citrulline + NH(3). {ECO:0000256|SAAS:SAAS00533843}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway: PATHWAY: Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 1/2. {ECO:0000256|SAAS:SAAS00533834}.
Active site: ACT_SITE 391 391 Amidino-cysteine intermediate. {ECO:0000256|PIRSR:PIRSR006356-1}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): arcA_1
Gene names (synonym):
Mass: 46,396
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; arginine deiminase activity [GO:0016990]; arginine catabolic process to ornithine [GO:0019547]
Gene ontology IDs: GO:0005737; GO:0016990; GO:0019547
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the arginine deiminase family. {ECO:0000256|SAAS:SAAS00533823}.
Protein families: Arginine deiminase family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99618
UniPathway: K01478
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR003876;IPR033199
PIRSF: PTHR12737
PRINTS: PIRSF006356
PROSITE: PR01466
Pfam:
ProDom:
SMART:
SUPFAM:
TIGRFAMs:
440123-441335(-)

>nucleotide sequence
TTATTTTTTAATCGGATCTCGGTATAGCGGCATACTCATACAACGCGCACTCCCCATCCC
CAATGATAATTGGTCACCATTCCAACTGATAACTTTAACACCAGCATCTCTTAGCGTTTG
GTTAGTCTTATAATTGCGATCATAACCAACAACAACACCTGGTTGGATCACTAAAAAGTT
AGTCGCATCAAAGTTGGTTTCAACATCGATCTCAATTTGGGTTGAATCTTCACCAGCAAC
CGGAATTAAAGTCGCTTTTTTACCAATAACCATTGATAAAAACCCTTCTAGTGATTCATT
TAACTCTCTTCAAATTAAAGTTGGATGTATCAGATCGATCTCTCAGATCTTTAATACTCC
CATCATATTAGGTGAGTATAAGAACTTATCATAATCTAGCATCGTTAATCAAGTATCTAA
ATGCATTAAATTACTCATCTTAGGGACATTAATTGCATAGATCTTTTCAAAGCTAGTTTC
ATCATTTTGCCTTAATTTTTCAGCTAATGACTGAATTGCTTTTTTCTCAGTTCGTTCTGA
AACACCGATCACTAAGGTCTTATCATCATAAACAAATAGATCTCCACCCTCGATACTGTA
TTTATCTTCTCTTGAATAGTATTTAGGTGCATTTTTATATTCTGGATGGTGGGAGAAGAT
AAAATCAGCAAAGATCGTTTCGCGTTTTCTTGTTGGATGAAACATTGAGTGTAAGGTAAT
TCCCTTACCAATACTAGCAAACGGATCTCTTGTAAAATACAGATTGGGCATTGGATCTGC
TACTAATTCAACTTCAGATTGTATCCCCACTTCTTTAGCTAAGATCCCAGACATCATCTT
GCGAATCATAACTTGTGGGTTGGTTGCTAAACTTTTTAGATAATCATAAACCTTAAGACG
ATTAATCTCAGATAAAACCGGAAGACATTCATCTAACCAACGGTTGATGAACTCTTCTTG
GATCTTGCTATTTACTGCTTGAAACGTCTGTGCTGTTAAAGTTGATAATTGCACGCATTC
AACATCATGATCTTCTAATAACTTAATGAAAGTTTCATGTTCTTGTCTAGCTTTGATCGG
GTTAAGTAAAGAACTAAATAAGAGTTCATCCAATCTTTGTGGGGTAACATAATCTAATTC
TTTACCTGGAGTGTGAACTAAAACTTTTCTTAGTTTGCCAATTTCACTATAAACTCTGAT
CTTATTAAACAT

>protein sequence
MFNKIRVYSEIGKLRKVLVHTPGKELDYVTPQRLDELLFSSLLNPIKARQEHETFIKLLE
DHDVECVQLSTLTAQTFQAVNSKIQEEFINRWLDECLPVLSEINRLKVYDYLKSLATNPQ
VMIRKMMSGILAKEVGIQSEVELVADPMPNLYFTRDPFASIGKGITLHSMFHPTRKRETI
FADFIFSHHPEYKNAPKYYSREDKYSIEGGDLFVYDDKTLVIGVSERTEKKAIQSLAEKL
RQNDETSFEKIYAINVPKMSNLMHLDTWLTMLDYDKFLYSPNMMGVLKIWEIDLIHPTLI
WRELNESLEGFLSMVIGKKATLIPVAGEDSTQIEIDVETNFDATNFLVIQPGVVVGYDRN
YKTNQTLRDAGVKVISWNGDQLSLGMGSARCMSMPLYRDPIKK