GCW_02105

Uniprot: A0A0F6CKN0
Description: peptidase Lon (La)
EC number: 3.4.21.53
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Hydrolysis of proteins in presence of ATP. {ECO:0000256|PIRNR:PIRNR001174}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 718 718 {ECO:0000256|PIRSR:PIRSR001174-1}.; ACT_SITE 761 761 {ECO:0000256|PIRSR:PIRSR001174-1}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 392 399 ATP. {ECO:0000256|PIRSR:PIRSR001174-2}.
Site:
Gene names (primary): lon
Gene names (synonym):
Mass: 92,009
Subunit structure [CC]: SUBUNIT: Homohexamer. Organized in a ring with a central cavity. {ECO:0000256|PIRNR:PIRNR001174}.
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]; serine-type endopeptidase activity [GO:0004252]; protein catabolic process [GO:0030163]
Gene ontology IDs: GO:0004176; GO:0004252; GO:0005524; GO:0005737; GO:0030163
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PIRNR:PIRNR001174}.
Protein families: Peptidase S16 family
Coiled coil:
Domain [FT]: DOMAIN 9 228 LON. {ECO:0000259|SMART:SM00464}.; DOMAIN 384 530 AAA. {ECO:0000259|SMART:SM00382}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS: S16.004
EnsemblBacteria KO: AHB99652
UniPathway: K01338
CDD:
Gene3D:
HAMAP: 3.30.230.10;3.40.50.300
InterPro:
PANTHER: IPR003593;IPR003959;IPR004815;IPR027065;IPR003111;IPR027417;IPR008269;IPR015947;IPR020568;IPR014721
PIRSF: PTHR10046
PRINTS: PIRSF001174
PROSITE:
Pfam:
ProDom: PF00004;PF05362;PF02190
SMART:
SUPFAM: SM00382;SM00464
TIGRFAMs: SSF52540;SSF54211;SSF88697

In one protein complex with GCW_02100 494538-496977(+)

>nucleotide sequence
ATGGCAACATCAAAATCAGTACAAAAAGCACCCTTATTAATCTCACGTAAGATGGTTGTA
TTTCCTTACAACCAATACGTTTTAAGCATTGGTCGAGCGCGATCAATGAAACTTATTAAA
AAGATCAAAGCTCAACTTATTGAAGAATCAAAAAAGACGAAGTCAGGCGAAGCTAAAAAA
GAGTTTGAAAAGATTTTGGTTGTTGTCCAAAAGAACGATAACATTGACAAGCCAACAGTT
AGTGATATCTACAAATACGGAACTTTATGTGAGATAACTAGAATTAATGAAGAGGTTGAT
CAAGAAACGGGTGAACTGACTTATGAAGTTTCAATCCGTGGTATCGAACGGATTAAGATT
AGTACATCAAGTCTAAAAAACGTTTCACTAGAAGATTATATCGACCCAATTAGTTATTCG
ATCTGCAAAACTTATTTATCAATTAAACCTGATGAATTATGAGACACAATTCAAAAAGAA
GGTGTTTTTGATGAAGCTGATCTAAAAGAGATGGCAAAAACTGATCTATCAACAAGAGAG
TTAGATAAGATCTCATTAAGTCTAGCAGCTAATGCTAATGCCACTTTTGGTTCTGAACTA
TTATCAGAACATAATAAACAAGCAATCTTAGAACGCGATGATATTAAAGAACGTTTTGAT
CTTTACTTTAAGATCTGAAGAAAGATCCAATCTAATATCAAAGCCAACGAACGTAACGAA
GATATTAAACAAGTTGAACGAATGATCGAGCTGAAGATGAAAAAGCAGCTGACCAAACAA
CAAAATGAATATTATCTTCGTGAAAAACTAAAAACGATTAAAGAAGAGCTTGGTGATATC
ACTAATAAAGAAGATGATGTTGAATCGATCCGAGCTAAGATTAAAGCTAATCCTTACCCT
CAACACATTAAGGATCGAATCTTAACTGAAATTAATCGTTATGAAGCAACCGCTCCTCTT
TCTCAAGAAGGTAATGTCATTAAAACTTATTTAGATTGATTAATCAACTTACCTTGATGA
CAAACTAAAGAAGATAATTTTGAGATCGAAAAAGTAACCAAAACTTTAGATAATAACCAC
TACGGGTTATCTAAAGTTAAAGAAAAGATCATCGAATACTTAGCATTAGCGATGCGTTCA
AAAAATGCTAAAGGGCCAATTATGTGTTTAGTAGGTCCTCCAGGAGTGGGGAAATCATCT
TTAGCTAAATCGATCGCTGAAGCACTTAATAAAGAGTTTGTTAAGATCTCACTTGGTGGG
GTGCATGACGAATCTGAGATCCGTGGTCACAGAAGAACTTATGTTGGTTCAATGCCTGGT
AGAATCATCAAGGGAATGAAAAAAGCTGGGGTGATTAACCCATTATTCTTATTAGATGAG
ATCGACAAGATGGGTCAATCAGTTAATCATGGTGATCCAACTGCAGCATTACTTGAAGTG
TTAGATCCTGAACTAAATAACAAGTTCAATGATAACTACATTGAAGAAGATTATGATCTA
TCAAGTGCAATGTTTGTGGCGACTGCTAACTATGTTGAAGGGATCCCAGAAGCACTTTAT
GATCGGATGGAGATTATTGAACTAACTTCATACACTGAGCATGAAAAGTTATCAATTGCT
AAGAATTATCTAATCCCAAGATCACTTAAAGAAGCAGAACTTTCTGATAGTGAGATCAGT
TTTAGTGATGAAGCGATTATGTACATCATTAAGCACTTCACTAAAGAAGCTGGCGTTAGA
AGTCTTGAACGGGTATTAAAACAGATCGTTCGTAAGTTCTTAGTAGCAAGTCTAAGAGAT
AAGAAACTAAAAAAACAAGTAATCAATATCCCAGAAGTAAAACACTACTTGAAAAAAGAA
GTGTTTGATTACACCCAAAAAGATGAATTCTCAATCCCTGGGATTGTGAATGGGATGGCT
TACACCCAGTATGGGGGTGATCTATTACCAATCGAAGTAAGTATTGCTCAAGGTGGTAAG
GGTAATGTGGTGATTACAGGTAACTTAAAAGAAACGATGAAAGAATCAGTTAACGTTGCT
TTAGGTTATGTAAAAGCCAATGCTGCAGAATTTGGTATTGATTATGAGATCTTCCAAAAG
GTTGATCTACACATTCACGTACCAAGTGGTGGGATTCCAAAAGATGGTCCAAGCGCAGGG
ACAGCATTAACAACAGCGATCATCTCAGCGTTCACCAATAAAAAAGTAAGCCCATCAGTA
GCAATGACTGGTGAAATCACTTTAAGAGGTAAGGTTTTACCGATCGGTGGGGTAAAAGAA
AAAACGATCTCAGCTCACCGTGGTGGAGTTCGTACGATCTTCTTACCAGAAAAAAATGAA
AACCACCTTGATGAGGTTCCAAAAGAGATCTTAAAAGATTTAGAGATTATTCCTGTTAAG
GAATACAAAGAAATTTATAAAAAGCTCTTTTGTAAATAG

>protein sequence
MATSKSVQKAPLLISRKMVVFPYNQYVLSIGRARSMKLIKKIKAQLIEESKKTKSGEAKK
EFEKILVVVQKNDNIDKPTVSDIYKYGTLCEITRINEEVDQETGELTYEVSIRGIERIKI
STSSLKNVSLEDYIDPISYSICKTYLSIKPDELWDTIQKEGVFDEADLKEMAKTDLSTRE
LDKISLSLAANANATFGSELLSEHNKQAILERDDIKERFDLYFKIWRKIQSNIKANERNE
DIKQVERMIELKMKKQLTKQQNEYYLREKLKTIKEELGDITNKEDDVESIRAKIKANPYP
QHIKDRILTEINRYEATAPLSQEGNVIKTYLDWLINLPWWQTKEDNFEIEKVTKTLDNNH
YGLSKVKEKIIEYLALAMRSKNAKGPIMCLVGPPGVGKSSLAKSIAEALNKEFVKISLGG
VHDESEIRGHRRTYVGSMPGRIIKGMKKAGVINPLFLLDEIDKMGQSVNHGDPTAALLEV
LDPELNNKFNDNYIEEDYDLSSAMFVATANYVEGIPEALYDRMEIIELTSYTEHEKLSIA
KNYLIPRSLKEAELSDSEISFSDEAIMYIIKHFTKEAGVRSLERVLKQIVRKFLVASLRD
KKLKKQVINIPEVKHYLKKEVFDYTQKDEFSIPGIVNGMAYTQYGGDLLPIEVSIAQGGK
GNVVITGNLKETMKESVNVALGYVKANAAEFGIDYEIFQKVDLHIHVPSGGIPKDGPSAG
TALTTAIISAFTNKKVSPSVAMTGEITLRGKVLPIGGVKEKTISAHRGGVRTIFLPEKNE
NHLDEVPKEILKDLEIIPVKEYKEIYKKLFCK