GCW_02740

Uniprot: A0A0F6CKX5
Description: branched-chain alpha-keto acid dehydrogenasesubunit E2
EC number: 2.3.1.-
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor: COFACTOR: Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088; Evidence={ECO:0000256|RuleBase:RU003423};
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): aceF
Gene names (synonym):
Mass: 46,062
Subunit structure [CC]:
Gene ontology (GO): transferase activity, transferring acyl groups [GO:0016746]; metabolic process [GO:0008152]
Gene ontology IDs: GO:0008152; GO:0016746
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family. {ECO:0000256|RuleBase:RU003423}.; SIMILARITY: Contains lipoyl-binding domain. {ECO:0000256|SAAS:SAAS00100665}.
Protein families: 2-oxoacid dehydrogenase family
Coiled coil:
Domain [FT]: DOMAIN 1 76 Lipoyl-binding. {ECO:0000259|PROSITE:PS50968}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99747
UniPathway: K00627
CDD:
Gene3D:
HAMAP: 3.30.559.10
InterPro:
PANTHER: IPR003016;IPR001078;IPR000089;IPR023213;IPR011053
PIRSF:
PRINTS:
PROSITE:
Pfam: PS50968;PS00189
ProDom: PF00198;PF00364
SMART:
SUPFAM:
TIGRFAMs: SSF51230

In one protein complex with GCW_02735 GCW_02745 GCW_02750 GCW_02755 GCW_02760 GCW_02720 648922-650251(-)

>nucleotide sequence
TTAAATTAGTAAACCATCAAGATTTTCAACGATTTCTTTTAATGTTTTAGCAAATCTACC
TATATCAGCACCATCGATTCATCTGTGGTCAGCTGCAATTGTAATTGGCATAATTTGCTT
AATTACGATTTGGTTTTCAGGAGTTCTTGCTAATTTTTCTTCTATTGTACCAGTAGCAAT
AATTGCAACTTCTGGGAATTTAATAATTGGTGTACCAAATAAAGCCCCGATTGAACCAAA
GTTAGTTACACTGATTGTACCATCAGCTAAATCAGCTAAACCGATCTTCTTAGAGCGAGC
TTTTTCAGCTAAATTGTTTACTTCTCTAGCAAGTTCAATCACTGATTTGTCTTGAGCTGA
TTTAATGTTAGGAACCATTAAACCATCAGCAGTATCAACAGCAATACCTAAGTTAATCTT
TTTCTTTAATACTAAGCGGTTGCTAGCTTTGTCGTAGTGAGAGTTGAAAACTGGGTGAGC
AACTACAGCTTTAGTAATTGCTTTTAATAAGAATGGTAAGAATGATAATTTAACATTGTA
ACTTGCTAATACAGCATCCTTAACTTGCTTACGGTATGATACTAATTTAGTTACATCAAA
GTTGAATGTTAAAACAGTTGCTGGAATTTCTTCGTGAGCAGTAATCATTGCTTTAGCAAT
TGCTTTTCTAATTGATGTAATTTCTTTGTAAGTTTCGTTATCGTTTGCAGCTACACTAGC
AGCTGGTGAACTTTGTTGAGCTGATGCAAATACATCGCTTGAGAATACTTTAGCACCGTT
AGCAGGTGTTACGTTGTGTAAATTTACATTTAAATCACTAGCAACAGCTTGAGCTAAAGG
AGTCGCAACTGGAACTGGAGTTGGCGCAAAAGCTGTAGCAGGAGCTGGTGTTGGAGTACT
TGCAGCGCGTTGATCACCAAATAATCCAAATAAAGTGTTTGAAACTTTAACTTCACCTAC
AACTGAAGCACCACCACCACTAGGAGCAGCTTCAGCAGGAACAGGAGCTGGTGTAACAGC
TGGAGTAGGAGCTACAAAAGCTGGAGTAGCAGGCGCAGCAGCTGGAGCTGATGCAGCAGC
TGGAGCTGATGAACCATCACCGTTTAAAACAAGCATTACTTCACCAACGTGAACAGTTTG
TCCTACTGATGCAAGGATCGCAGTAACTTTTCCACCTTCAGGAGCTGGTAAGTCAGTTGT
AACCTTATCAGTTTCAACTGAAAACATCGGGTCACCTTCTTTAATTGTGTCACCTACTTT
AACATAGATTTGAGCAACAACACCTTCATGTAGCCCTTCACCAACGTCTGTAAATTTATA
TTCAAACAT

>protein sequence
MFEYKFTDVGEGLHEGVVAQIYVKVGDTIKEGDPMFSVETDKVTTDLPAPEGGKVTAILA
SVGQTVHVGEVMLVLNGDGSSAPAAASAPAAAPATPAFVAPTPAVTPAPVPAEAAPSGGG
ASVVGEVKVSNTLFGLFGDQRAASTPTPAPATAFAPTPVPVATPLAQAVASDLNVNLHNV
TPANGAKVFSSDVFASAQQSSPAASVAANDNETYKEITSIRKAIAKAMITAHEEIPATVL
TFNFDVTKLVSYRKQVKDAVLASYNVKLSFLPFLLKAITKAVVAHPVFNSHYDKASNRLV
LKKKINLGIAVDTADGLMVPNIKSAQDKSVIELAREVNNLAEKARSKKIGLADLADGTIS
VTNFGSIGALFGTPIIKFPEVAIIATGTIEEKLARTPENQIVIKQIMPITIAADHRWIDG
ADIGRFAKTLKEIVENLDGLLI