GCW_02810

Uniprot: A0A0F6CKY8
Description: RNA pseudouridine synthase
EC number: 5.4.99.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: RNA uridine = RNA pseudouridine. {ECO:0000256|RuleBase:RU362028}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Responsible for synthesis of pseudouridine from uracil. {ECO:0000256|RuleBase:RU362028}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rluA_2
Gene names (synonym):
Mass: 39,476
Subunit structure [CC]:
Gene ontology (GO): pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; pseudouridine synthesis [GO:0001522]
Gene ontology IDs: GO:0001522; GO:0003723; GO:0009982
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the pseudouridine synthase RluA family. {ECO:0000256|RuleBase:RU362028}.
Protein families: Pseudouridine synthase RluA family
Coiled coil:
Domain [FT]: DOMAIN 14 91 S4 RNA-binding. {ECO:0000259|PROSITE:PS50889}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99760
UniPathway: K06179
CDD:
Gene3D:
HAMAP: 3.10.290.10
InterPro:
PANTHER: IPR020103;IPR006225;IPR006224;IPR006145;IPR002942
PIRSF:
PRINTS:
PROSITE:
Pfam: PS01129;PS50889
ProDom: PF00849;PF01479
SMART:
SUPFAM: SM00363
TIGRFAMs: SSF55120
667320-668313(-)

>nucleotide sequence
TTATTTTTCTTGGTAAGGATTGGGGTGCAGTTGGCTATGAAACCAAGCTGGTGACTTGGT
TTGATATTGATTCTGGTCTAAGTACTTCAAGATGAAATCTTGATCATAATTAGCTAGATC
AAAGATGATCTTGTAACTATGTAGTAGTTGGTGTTTAAAATTACCTTGGTTATTTTGGTA
TTGCTTTTTAGCATACTTATAATCACCCACCACTGGGTGGTTTATGAATGCTAAATGAGC
TCTGATCTGATGGGTTCGTCCCGTGATTAGTTCAACATCTAATAGAGTGTAGTTTTGTTT
TTTAAAGTAATAAAGGGTCTGATAACGGGTGATAATTATTTTATTATCGTTCGTTTTTTC
TTTTTGGATACTAACTAAAGATCGGTTGGGATCTTTAGTTAGATAAGCTGTTAGTGTCGC
TTTTTTGGGATTAATCTCACCGTGAACTAAACAATGATAAAATTTTTTCAGATCACGGTT
TTTAATGATCTGGTTGAGCGCTTGTTGAGCTTTAAGATTTTTTGCTCCTAGCATAATCCC
AGTCGTGTAGGTATCAAGCCGATTAACAATACTTGGTAAATAAGCTTGATTATTTAAATA
ATCATATTGATTAGATTTAACCAGATAATGAACCAAGCGATTTTGCATATGATCATATTG
GCTTGGTTCATTAGTTTGTTGGGCTGAGATTCCCAATGGTTTTTCAAAGATCACTAAATT
CTCATCTTCATAGATCAGATCTAATTCTGGTTTAGCTTTGAAAAACTCTGGTGCTTTTTT
CTTATGATCTGTTCTTAAGAAATCATAATAAGTGATCTTATCATTCACCCTTAAGATGTA
ATCAAAATCAATTCGTTGATTATTAACCGTAATATCTTTCTTACGGATCATCTTATAAAT
ATTAGTTCTTGTGTAGTTTTTTAAATACTTAAATAAGAACTTATCAATCCTAATACAATC
ATCTACTGATTTGATAACGATCGTTTTTTTCAT

>protein sequence
MKKTIVIKSVDDCIRIDKFLFKYLKNYTRTNIYKMIRKKDITVNNQRIDFDYILRVNDKI
TYYDFLRTDHKKKAPEFFKAKPELDLIYEDENLVIFEKPLGISAQQTNEPSQYDHMQNRL
VHYLVKSNQYDYLNNQAYLPSIVNRLDTYTTGIMLGAKNLKAQQALNQIIKNRDLKKFYH
CLVHGEINPKKATLTAYLTKDPNRSLVSIQKEKTNDNKIIITRYQTLYYFKKQNYTLLDV
ELITGRTHQIRAHLAFINHPVVGDYKYAKKQYQNNQGNFKHQLLHSYKIIFDLANYDQDF
ILKYLDQNQYQTKSPAWFHSQLHPNPYQEK