GCW_02890

Uniprot: A0A0F6CL01
Description: elongation factor P
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. {ECO:0000256|HAMAP-Rule:MF_00141}.
Pathway: PATHWAY: Protein biosynthesis; polypeptide chain elongation. {ECO:0000256|HAMAP-Rule:MF_00141}.
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): efp
Gene names (synonym):
Mass: 21,267
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; translation elongation factor activity [GO:0003746]
Gene ontology IDs: GO:0003746; GO:0005737
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the elongation factor P family. {ECO:0000256|HAMAP-Rule:MF_00141, ECO:0000256|RuleBase:RU004389}.
Protein families: Elongation factor P family
Coiled coil:
Domain [FT]: DOMAIN 69 123 EFP. {ECO:0000259|SMART:SM01185}.; DOMAIN 131 186 Elong-fact-P_C. {ECO:0000259|SMART:SM00841}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99773
UniPathway: K02356
CDD:
Gene3D:
HAMAP: 2.30.30.30;2.40.50.140
InterPro: MF_00141
PANTHER: IPR015365;IPR012340;IPR014722;IPR020599;IPR013185;IPR001059;IPR011768;IPR008991
PIRSF:
PRINTS: PIRSF005901
PROSITE:
Pfam:
ProDom: PF01132;PF08207;PF09285
SMART:
SUPFAM: SM01185;SM00841
TIGRFAMs: SSF50104;SSF50249
685204-685771(-)

>nucleotide sequence
TTAGTTTGCTCTTGAGACATATTTACCGTCAACCGTTGATACGATTACTTTTTCTTTGGA
CTTAATAAACTGAGGAACTTCAATTACATAACCAGTAACTAAAGTCGCTTTTTTTAGTGC
ATTATTAACACTATTCCCTTGTACTGCGTCTTCAGCATAATCGATCTCAATCACAACTTG
ATCAGGTAAATTTACCCCTAAGATCTCATCTTCATAACGCATGATTAATGCTTCAGTGTT
CTCAGTAATGAAATTCTTTTCATACTCTAGTAACTTAGCAGGTACTTCGATCTGTTCATA
AGTTTCGTTGTTCATGAAAACAAAACTGTTTTGATCTTGGTAAACAAACGACATTTTTAT
TTTTTCAATGTTAGCTTGTTCTAGTTTCATCCCGGTTAATACTTCTGTAGTAATCGAACC
AGTCCGTAAATTTTTCACTTTACATTTAACAATGCCTTCGCGCATTGCGGTTTTGTTAAA
TGAGTTTTCAATCACCAAATAAATTTTGCCATCTAAAGTAAATGTATGACCACTTCTAAG
GTCTTTTGCGTGAATAATTGATGCCAT

>protein sequence
MASIIHAKDLRSGHTFTLDGKIYLVIENSFNKTAMREGIVKCKVKNLRTGSITTEVLTGM
KLEQANIEKIKMSFVYQDQNSFVFMNNETYEQIEVPAKLLEYEKNFITENTEALIMRYED
EILGVNLPDQVVIEIDYAEDAVQGNSVNNALKKATLVTGYVIEVPQFIKSKEKVIVSTVD
GKYVSRAN