GCW_03255

Uniprot: A0A0F6CL62
Description: ribose-phosphate pyrophosphokinase
EC number: 2.7.6.1
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. {ECO:0000256|RuleBase:RU004325}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): prsA
Gene names (synonym):
Mass: 38,106
Subunit structure [CC]:
Gene ontology (GO): kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; ribose phosphate diphosphokinase activity [GO:0004749]; nucleoside metabolic process [GO:0009116]; nucleotide biosynthetic process [GO:0009165]; ribonucleoside monophosphate biosynthetic process [GO:0009156]
Gene ontology IDs: GO:0000287; GO:0004749; GO:0009116; GO:0009156; GO:0009165; GO:0016301
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family. {ECO:0000256|RuleBase:RU004324}.
Protein families: Ribose-phosphate pyrophosphokinase family
Coiled coil:
Domain [FT]: DOMAIN 8 123 Pribosyltran_N. {ECO:0000259|Pfam:PF13793}.; DOMAIN 163 270 Pribosyltran. {ECO:0000259|Pfam:PF00156}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99834
UniPathway: K00948
CDD:
Gene3D: cd06223
HAMAP: 3.40.50.2020
InterPro:
PANTHER: IPR000842;IPR029099;IPR000836;IPR029057;IPR005946
PIRSF:
PRINTS:
PROSITE:
Pfam: PS00114
ProDom: PF00156;PF13793
SMART:
SUPFAM:
TIGRFAMs: SSF53271
782166-783189(-)

>nucleotide sequence
TTATTCTATTTCTTTTAGAATTTTCTTTAGGTTTGGTGATTTTACTCATTCTTGATAAAT
TGTATAAACATCACTGATAGAACCACCATTAATATATTTATCTAAAACTAAACTATAAAA
GTGGTCTAATTTAACAACTTTAAATTGTGGTTTCTTTTTTAAATTCTTTTCAGTTTGATC
AATAGTATCAGTTATATAAACTTTATTGATTTCTTTTTTCTTATAACATTCATCGAATAA
TTCGATGGCATTTTTATTGAATAAACCATGTGTAGCCATTACTAGAACTGTCTTAGCTTT
TTGTTTTTTTAGTAATTTAGCTGCCGAGATAATCGTTCCACCGGTATCGATCATATCATC
AACAAGAATACAGCATTTATTCTTCACTTCACCAAGAATATTGATTGATTCAGCTACATT
TGGTTTAGGTCTTCTCTTATCAATAATAGCTAAAGGAACATTAATTGATTCAGCAATTTT
TCTAGCTCTTTTAACACCACCATAATCTGGTGATATAACTACTAAATCGTCAATTTTATT
ATCCACTAATACGTGAGATAATAAAACAAAAGAAGCTTTTAGAGTATCAACTGGGATATC
AAAGAAACCTTGGGTTTGGTCGCTGTGAATATCAGTTAATGTTACTCTAGTAGCTCCTGC
TTTGGTTAGTAAATCTGCAACTAGTTTCGAGGTAATTGGTTCTCTACCAGCCGATTTTCT
ATCTTGTCTTGCATAACCATAATATGGGATTAATGCAGTAATCGATTTTGCAGAGGCTCT
TTTAGCAGAATCAATAGCAATTAACAATTCCATTAAATTATCATTTACTGGCGAGTTAGT
CGATTGAATAAAAACAACATCTTTATTTCTCAGGGTACAATCAGGCCTAACAAAGATTTC
GTCATCAGCAAATTTTTGAATCACGATTTCACCAGGTTTCATTGACAATCTTCTACAGAT
TGAATCAGTTAATTTTTTAGCGGCCGACAGCCCAAAGATAATATGATTAGATTTAAAGTT
CAT

>protein sequence
MNFKSNHIIFGLSAAKKLTDSICRRLSMKPGEIVIQKFADDEIFVRPDCTLRNKDVVFIQ
STNSPVNDNLMELLIAIDSAKRASAKSITALIPYYGYARQDRKSAGREPITSKLVADLLT
KAGATRVTLTDIHSDQTQGFFDIPVDTLKASFVLLSHVLVDNKIDDLVVISPDYGGVKRA
RKIAESINVPLAIIDKRRPKPNVAESINILGEVKNKCCILVDDMIDTGGTIISAAKLLKK
QKAKTVLVMATHGLFNKNAIELFDECYKKKEINKVYITDTIDQTEKNLKKKPQFKVVKLD
HFYSLVLDKYINGGSISDVYTIYQEWVKSPNLKKILKEIE