GCW_03315

Uniprot: A0A0F6CL73
Description: purine nucleoside phosphorylase
EC number: 2.4.2.1
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. {ECO:0000256|SAAS:SAAS00035253}.; CATALYTIC ACTIVITY: Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. {ECO:0000256|SAAS:SAAS00035263}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): deoD
Gene names (synonym):
Mass: 26,590
Subunit structure [CC]: SUBUNIT: Homohexamer. {ECO:0000256|SAAS:SAAS00035157}.
Gene ontology (GO): purine-nucleoside phosphorylase activity [GO:0004731]; nucleoside metabolic process [GO:0009116]
Gene ontology IDs: GO:0004731; GO:0009116
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the PNP/UDP phosphorylase family. {ECO:0000256|SAAS:SAAS00547350}.
Protein families: PNP/UDP phosphorylase family
Coiled coil:
Domain [FT]: DOMAIN 15 233 PNP_UDP_1. {ECO:0000259|Pfam:PF01048}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99845
UniPathway: K03784
CDD:
Gene3D:
HAMAP: 3.40.50.1580
InterPro:
PANTHER: IPR004402;IPR018017;IPR018016;IPR000845
PIRSF: PTHR21234
PRINTS:
PROSITE:
Pfam: PS01232
ProDom: PF01048
SMART:
SUPFAM:
TIGRFAMs: SSF53167
793286-793997(-)

>nucleotide sequence
TTATAGTTTATTAGCCACATTAAGTGCTAACTCCATCATATTTTTAAATGTTGTTTGGCG
TTTCTCTGGACTCATTGATTCATGGGTAACTAATGAGTCAGAGACCGTTAGGATCGTCAT
TGCATGCTTTTTAGCTTTTTGTGCATTAGCATTCAAAGCAAAACCTTCCATCTCTACAGC
GATCGCATTTCATTTTTCATTAGCTTGCTTGGGAGTGTATAAGGTTTGATAAAAAGCCTC
TTCACAGATCACTAACCCTTCATGGTATTTGATCTTTAATTCATCAGCTGTTTTTCTTGA
TAACTCTAATAATTTAGCTGAAGGGTAATTAGTTTTATTCACGACATCAACCCCGATTAG
CATCGCATAAGGTGATTCGCTATAAGCCTTGCTTTCTAAGATCACATCACCTAAGTTAAG
ATCTTTAACTAAAGCACCGCATGAACCAACACGAATAATATTTTCAACATCATAAAAATT
ATAAAGCTCGTGGGTGTAGATCCCAATTGAAGGATTACCCATCCCATGACCCATAACTGT
TACTAATTTGTTCTTATATTTGCCAGTATAAGCAAACATATTTCTTACTTCATTAACTAG
TTTATAGTCTTCTAGAAATGTTTCTGCAATCCATTTTGCTCGTAATGGATCACCAGGCAT
AATTACTGTTTTAGCGATCTCTTCTTTTTTTGCTTTAATATGTGGAGTCAT

>protein sequence
MTPHIKAKKEEIAKTVIMPGDPLRAKWIAETFLEDYKLVNEVRNMFAYTGKYKNKLVTVM
GHGMGNPSIGIYTHELYNFYDVENIIRVGSCGALVKDLNLGDVILESKAYSESPYAMLIG
VDVVNKTNYPSAKLLELSRKTADELKIKYHEGLVICEEAFYQTLYTPKQANEKWNAIAVE
MEGFALNANAQKAKKHAMTILTVSDSLVTHESMSPEKRQTTFKNMMELALNVANKL