GCW_03575

Uniprot: A0A0F6CLB9
Description: glucose-6-phosphate isomerase
EC number: 5.3.1.9
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-phosphate. {ECO:0000256|HAMAP-Rule:MF_00473, ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00500531}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway: PATHWAY: Carbohydrate biosynthesis; gluconeogenesis. {ECO:0000256|HAMAP-Rule:MF_00473}.; PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. {ECO:0000256|HAMAP-Rule:MF_00473, ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00500567}.
Active site: ACT_SITE 419 419 {ECO:0000256|HAMAP-Rule:MF_00473}.
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): pgi
Gene names (synonym):
Mass: 48,726
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]
Gene ontology IDs: GO:0004347; GO:0005737; GO:0006094; GO:0006096
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the GPI family. {ECO:0000256|HAMAP-Rule:MF_00473, ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00546812}.
Protein families: GPI family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99891
UniPathway: K01810
CDD:
Gene3D:
HAMAP:
InterPro: MF_00473
PANTHER: IPR001672;IPR018189
PIRSF: PTHR11469
PRINTS:
PROSITE: PR00662
Pfam: PS00765;PS00174;PS51463
ProDom: PF00342
SMART:
SUPFAM:
TIGRFAMs:
855725-857012(-)

>nucleotide sequence
TTATTCTTTTAGTAATTTAAACATTCTTTGTTTGTAATCCTCAACCCCTGGTTGGTTATA
AGGATCATGACCTAATAGTAGTGCTGATACTGAAGTTGCTACACACAACCAGAAGTAAAG
ATAACCAAAGCCATAAGCACTATTTTCTTTAACATCAATCTCAATAATCGGAACACCAGC
AGAAGCGTGAGCTTGTTTGGTTGCTTCACACGCAACATAGTTAAGTTGGTTAACTGATTT
CTTGGTTAGATAATCTAGTTGGTCATCATTATTAAACTCTGAGTTTTTTAACTTTAGTTT
GTTCTTATTAGCTTTTTCAAATGAGAACACTGTTTCAAAAAAGATCTTCTTACCATCTTG
ATATAGTTGGCCCATTGAGTGTAAATCAGTCGTAAACACGGAGTATGTTGGGAATAATGA
ATTTAATGATTTACCTTCACTTTCACCAAACAGTTGGCGGTGTTGCAACATTAAGTATTC
GTGTTGTTCTTCATAAGTGATTGCAATCTCAACATCTTTTTTCATCTCTGTGTAAAGATA
ATGTCTTAGTGCAGCATAAGTATAAGCTGAGTTCTTCTTTAGTTCACTAGAAGCAAATAG
ATCAGCTTTGGCTTTTTTAGCCCCTTCGATTAGTTGCTTATAATCAGCCCCTACAAGACC
AGCAACTAATAATCCACTTGGTGTGATCGTTGAAAATCTACCCCCGATATCAGAGTAAAT
TGGCAACATCTCATATTTATTTTTAACCGCTATATCGTGAAGCACACCTTTTTTAGGATC
AGTAATCGCAACAATTCTTTTTTGTGCTTGTTCCCCATATTGTTTGTATAAAGCTTCACG
GAACAGTTTAAAACCAACTGAAGGTTCTAAAGTTGTTCCTGATTTAGAGATCACAACGAT
CCCCCAGTTCTTATCCTTAATTTCTTCTAATAATTTTAAGAATGAATTTTCACTTAAACT
GCGAATAAAGTGAATCTGTCTTTTTTGTTCACTAGGCAAATAAGCAACAACATCTAAGAT
CGCTTTAATCCCTGTAAACGATCCACCGATCCCAATAACAACAACATCTGTTACTTTTAA
TTTATCTCATTCAGCAATCTTATTATCAATACTCTTATAGATCTTGGTGTGGTCTTGATC
AACATAATCAATCCAACCTAACATATTAGCACTTGGTGTCTTTTTATTTTTTAATTGACT
AAAAATTTCATCAAGTTTTGCTTGATAGTTTTTATCTAATTTCTTATAGTCTAAACCTTT
AATAAGGTTGAAGGTTAATTTAATCAT

>protein sequence
MIKLTFNLIKGLDYKKLDKNYQAKLDEIFSQLKNKKTPSANMLGWIDYVDQDHTKIYKSI
DNKIAEWDKLKVTDVVVIGIGGSFTGIKAILDVVAYLPSEQKRQIHFIRSLSENSFLKLL
EEIKDKNWGIVVISKSGTTLEPSVGFKLFREALYKQYGEQAQKRIVAITDPKKGVLHDIA
VKNKYEMLPIYSDIGGRFSTITPSGLLVAGLVGADYKQLIEGAKKAKADLFASSELKKNS
AYTYAALRHYLYTEMKKDVEIAITYEEQHEYLMLQHRQLFGESEGKSLNSLFPTYSVFTT
DLHSMGQLYQDGKKIFFETVFSFEKANKNKLKLKNSEFNNDDQLDYLTKKSVNQLNYVAC
EATKQAHASAGVPIIEIDVKENSAYGFGYLYFWLCVATSVSALLLGHDPYNQPGVEDYKQ
RMFKLLKE