GCW_03725

Uniprot: A0A0F6CLE7
Description: peptidyl-tRNA hydrolase
EC number: 3.1.1.29
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA. {ECO:0000256|HAMAP-Rule:MF_00083, ECO:0000256|RuleBase:RU000673}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. {ECO:0000256|HAMAP-Rule:MF_00083}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): pth
Gene names (synonym):
Mass: 20,704
Subunit structure [CC]: SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00083}.
Gene ontology (GO): cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]
Gene ontology IDs: GO:0004045; GO:0005737; GO:0006412
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the PTH family. {ECO:0000256|HAMAP-Rule:MF_00083, ECO:0000256|RuleBase:RU004320}.
Protein families: PTH family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHB99919
UniPathway: K01056
CDD:
Gene3D: cd00462
HAMAP: 3.40.50.1470
InterPro: MF_00083
PANTHER: IPR001328;IPR018171
PIRSF: PTHR17224
PRINTS:
PROSITE:
Pfam: PS01195
ProDom: PF01195
SMART:
SUPFAM:
TIGRFAMs: SSF53178
887101-887653(+)

>nucleotide sequence
ATGAAACTTATTGTCGGTTTAGGCAATCCTGGGTTTGAATACGAGCACACTCGTCATAAT
ATCGGATTTAAGATTATTGACAAGTTATTAGATGTTTTAAATTTGGAATTAAATAAATCC
CAATTTAATGGCCTTTATGTCAAGCATGATGATTTTATTATTGCCAAACCCTTAACTTAT
ATGAACTTGTCGGGTAATTTTATCCGTCAACTAGTTAACTTTTATAAGATTCAGATCGAT
GATATCTTAGTAATCCATGATGAGTTAGCTTTTAATCTAGGAGTGGTGAGATTAAAGCAA
AACGGTTCAGCTAATGGTCAGAAGGGTGTGGCTAATATTATTAACCAGCTAGGCACACAA
AATTTCAAGCGCCTAAGGGTTGGAATTAAAAACGAAGATCTAAAAAATATTGCCTCATTT
GTTTTAAGTAAGTTTGCTCCTAACGAATTAATCTTATTAGAAAGCGCAATCGCTTCAGCT
AGTGTGATTGCTTATGATTTTCTTAAATCAAATAAGAGCTTTAGCAAATTAATGAATGAG
TACAACCAATAA

>protein sequence
MKLIVGLGNPGFEYEHTRHNIGFKIIDKLLDVLNLELNKSQFNGLYVKHDDFIIAKPLTY
MNLSGNFIRQLVNFYKIQIDDILVIHDELAFNLGVVRLKQNGSANGQKGVANIINQLGTQ
NFKRLRVGIKNEDLKNIASFVLSKFAPNELILLESAIASASVIAYDFLKSNKSFSKLMNE
YNQ