GCW_90093

Uniprot: A0A0F6CLS4
Description: C-terminal domain of GMP synthetase protein
EC number: 6.3.5.2
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity: CATALYTIC ACTIVITY: ATP + XMP + L-glutamine + H(2)O = AMP + diphosphate + GMP + L-glutamate. {ECO:0000256|SAAS:SAAS00496552}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway: PATHWAY: Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1. {ECO:0000256|SAAS:SAAS00496560}.
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 10,264
Subunit structure [CC]:
Gene ontology (GO): ATP binding [GO:0005524]; GMP synthase (glutamine-hydrolyzing) activity [GO:0003922]; pyrophosphatase activity [GO:0016462]; GMP biosynthetic process [GO:0006177]
Gene ontology IDs: GO:0003922; GO:0005524; GO:0006177; GO:0016462
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Contains GMPS ATP-PPase (ATP pyrophosphatase) domain. {ECO:0000256|SAAS:SAAS00496550}.
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 4 90 GMPS ATP-PPase (ATP pyrophosphatase). {ECO:0000259|PROSITE:PS51553}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHV85376
UniPathway:
CDD:
Gene3D:
HAMAP: 3.40.50.620
InterPro:
PANTHER: IPR025777;IPR014729
PIRSF:
PRINTS:
PROSITE:
Pfam: PS51553
ProDom:
SMART:
SUPFAM:
TIGRFAMs:
21283-21556(+)

>nucleotide sequence
ATGCAAGCAAGAAAACTACAAGATTTTTTAATTAGCACAGTCACCTTATTAAGGGACACA
ATTAAGAATAAGAAAGCCATCATCCCTTTGAATGGTAGTGTGTTTTCTTTTGTATTAGCT
AAGATCACCAAGATTGCTTTAAATAAAAATCTGATCTGCATTTATATTGATAATGGGATG
ATGCGCCATAATGAAGTGGCTAACAAGATCCATTTTTTAGGGAAAAACTTGATCTTGAAG
TATGACATATTGATGCTAAAGAGTTGTTCTTAA

>protein sequence
MQARKLQDFLISTVTLLRDTIKNKKAIIPLNGSVFSFVLAKITKIALNKNLICIYIDNGM
MRHNEVANKIHFLGKNLILKYDILMLKSCS