GCW_90999

Uniprot: A0A0F6CLV7
Description: Chromosome segregation ATPase
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Required for chromosome condensation and partitioning. {ECO:0000256|HAMAP-Rule:MF_01894}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 33 40 ATP. {ECO:0000256|HAMAP-Rule:MF_01894}.
Site:
Gene names (primary): smc
Gene names (synonym):
Mass: 112,017
Subunit structure [CC]: SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
Gene ontology (GO): chromosome [GO:0005694]; cytoplasm [GO:0005737]; ATP binding [GO:0005524]; DNA binding [GO:0003677]; chromosome condensation [GO:0030261]; DNA replication [GO:0006260]; sister chromatid cohesion [GO:0007062]
Gene ontology IDs: GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0007062; GO:0030261
Chain:
Signal peptide:
Domain [CC]: DOMAIN: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
Sequence similarities: SIMILARITY: Belongs to the SMC family. {ECO:0000256|HAMAP-Rule:MF_01894}.
Protein families: SMC family
Coiled coil: COILED 183 224 {ECO:0000256|HAMAP-Rule:MF_01894}.; COILED 264 381 {ECO:0000256|HAMAP-Rule:MF_01894}.; COILED 571 647 {ECO:0000256|HAMAP-Rule:MF_01894}.
Domain [FT]: DOMAIN 417 536 SMC_hinge. {ECO:0000259|SMART:SM00968}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHV85409
UniPathway: K03529
CDD:
Gene3D:
HAMAP: 3.40.50.300
InterPro: MF_01894
PANTHER: IPR027417;IPR003395;IPR010935;IPR011890
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF06470;PF02463
SMART:
SUPFAM: SM00968
TIGRFAMs: SSF52540;SSF75553
213482-216434(+)

>nucleotide sequence
ATGTTATTTCTAAAAAAATTTCATGCCCAAGGGTTCAAATCTTATGCTGATAACATTAGT
TTCACATTTGATGAACATGTAACAGGAATTGTCGGTCCTAATGGGTCTGGTAAATCTAAT
GTTGTTGACGCCTTAAAGTGAGTGCTTGGGGAGCGTTCAATGAAGAACTTAAGAGGAAAA
ACGAGTGATGACGTTATCTTTTTTGGTTCCCAAGAAAAACCAGCATCTAAGTTTGCTGAA
GTCAACTTAACATTTGATAACTCTCAAGGTTATTTACATGATAAGCGCAAAGAGATTACA
GTTACTAGAAGGGTGTATCGTGGTAGCGGGGTATCAGAATACTTAATTAATAACGTACCA
TCATCACTTAAAGAAATTAACGATATTTTTCTTGATTCAGGTCTAACTAAAGGTTCGTTA
TGTATTATTTCACAAAACACCGTATCTAGTTTTATTGAAGCTAAACCAGAAGACCGAAGA
CAGATCTTTGAAGATGCTGCAGGGATTGGGCGTTATGCTAAGAAAAAAACAGACGCAATC
AGACAAATTGCACGAACCAACGATAATTTAAAAGAAATAACAACAATCGTTAACGAATTA
AATCGTGATCTTAAAAAATTAAATCAACAAGCAGAAAAAGCCAAACTATATGCTGAAACA
AAAGAAAAACTAAAAGATCTTGAAATAACACTATCAGTTAACGAATATTTAATCTCACAA
AAAGAGATTGAAACACTATCAGAACAGATTGCAAAAATCGATGAACGTTTACTAAAAAAC
GATCCCCAATTACAGATCAATCAAGAAAAGTTAGAAGCATTTAAAAAACGCTACAACAGT
GCAGACCAAAATGTACAAAAAATTCAGGACGAATTACAAAAAATTTATGACGAAATCGTC
CTATTAGAAAAACGTAATGTCTTTAATGATTTACAACTAAAATCGGATTTAGATTCTAAT
GATAAAAATAAGAAGATTAATGCGTTAGAACAACTACTAAAATCATCAGAAGAGCAATTA
AAAAAATACTTTGAATTAATCTCAACTTGAGAAGAAGAATTAAAAGAAAAAGATGTTGAT
AAAACTGATCTAGCTAACGAATTAGAAAATCTAAAAAAATCATTAGCCACTTTCCAAGTT
AAGCGCTACGAAGCTAACTTGCAAGTTCAGTTTTATCAAAATCAAAAGATTAACCAATTT
GCACAAGATGCTGGTGTGCGTACAGTATTAAATAATAAGGATGCCATTGGTGGTGTGCAT
GGGATTGTGCAAGACTTCATTAAGGTTGAACCTGAATATGAGTTGGCAATCTCAACTGCT
TTAAATAAAGCTGCTAAAAACATTATTGTAGATTCAAACCAAGATGCTATTAATGCTGTT
AATTTTTTAAAAGCAAATAAAGCTGGAAGAGCAACATTTTTACCACTAGCTAACCTAAAA
GATCGTGATGTTAAACCAGAACATTTAGAAGTGTTAGAACAAGTGGAAGGTTATCTAGGG
ATTGCTGCTAACTTAGTTAACTACCACGATCAATATGATCCAGCAATCCGCGCTTTATTA
GGTCAGATTATTATTGCTAGTGATCTTGAAGCTGCTACCAAAATCTCTAAATTTACATAC
CAACTTTATCGAGTGATCTCACTTGGTGGGGATATCGTTAATGCTGGTGGTGCGATTACT
GGTGGTGCTGAATCAAAACAAACACACAGTTTATTTAATCTTGATGAAAAGATTGATACG
CTTAAAAACGAACTTTTAGTTACCGAAAAAAATATTAACGAACTAAATAAAAAACTTGAA
CTCCTAACAGCTGATTACACTAAGAAAGATAAAGAATTTAACGAACAAAAGATCGCAATC
CAACGTTATCAAGACTTAATTGTGATCGAACAAAAAAAGCTTGACGATTACAAGATTCAA
TACGAACAATTAACTGATAAAACCTTTGATGGTAAAGATGTTAAATGAGATGATAAAAAG
ATCAAAGATAAACTGTTTAGTTTAGAAACTAAGAAAGCTACTTTAGTTCAAGATCTTAAG
ATCAATCAAGAAGCTAAAGATATGTATCAAAAACAAGTTAACCAACTTGAAAAAGACGTT
ACGCTCTTTTATAAAGAGATCGATGAAGATAAGAACGATAAATTAAAACGTCGTGAACAA
CTAACTAAACATGAAAACACGATCTACTTAGCTAAATCAAAGATTAATGAAGCTTATAAT
ATGGCAATTGAGTTTGCAATTGAAAACTACAATAAGCCATTGCCGATCTCTTTATCTCAA
GCAAGAAATGAAGTAGTAAAACTTCAAAGCACCCTAAATAATTTAGGGGCAATTAATATG
GAAGCGATCCAAGAGCTTGATATTAAAAAAGAGCGTTATGAAAAGCTTTATAGCCAACAA
CAAGAATTAATTAATGCTCGTGAACGGATTAATGAAGCAATAATTAGATTAGATGAAAAA
GCAATCTTTGAATTTGATCAATTAATTAATAACCTTAATAAGGAGTTACCTAAGACATTC
TATTACCTATTTGGTGGTGGTAATTGTGAGATTAGATATTCTAATCCTGAAGAAAAACTA
ACCAGTGGGATTGAAGTGTTTGCTTCACCTCCTGGTAAGAATATTGGGAACTTAAACTTA
CTATCAGGTGGTGAAAAAGCTTTAGTTGCTTTATCAGTTTTATTTAGTATTCTTAAAGTG
TCTTCATTCCCACTGGTTGTTTTAGATGAAGCTGAGAGTGCTTTAGATTTAGCTAACGTA
GAACGATTTGCTAATATCATTAAGAATTCATCTGATCAGACCCAATTCTTAATCATCACC
CACCGTGAAGGAACGATGGTTAAATGTGATAAGTTAATTGGGGCAACGATGCAAACTAAG
GGTGTGACTAAGATGTTATCAGTATCTTTACACCAAGCTAAAGATATGGCTGAAGAGATT
GAGAGTCAATAA

>protein sequence
MLFLKKFHAQGFKSYADNISFTFDEHVTGIVGPNGSGKSNVVDALKWVLGERSMKNLRGK
TSDDVIFFGSQEKPASKFAEVNLTFDNSQGYLHDKRKEITVTRRVYRGSGVSEYLINNVP
SSLKEINDIFLDSGLTKGSLCIISQNTVSSFIEAKPEDRRQIFEDAAGIGRYAKKKTDAI
RQIARTNDNLKEITTIVNELNRDLKKLNQQAEKAKLYAETKEKLKDLEITLSVNEYLISQ
KEIETLSEQIAKIDERLLKNDPQLQINQEKLEAFKKRYNSADQNVQKIQDELQKIYDEIV
LLEKRNVFNDLQLKSDLDSNDKNKKINALEQLLKSSEEQLKKYFELISTWEEELKEKDVD
KTDLANELENLKKSLATFQVKRYEANLQVQFYQNQKINQFAQDAGVRTVLNNKDAIGGVH
GIVQDFIKVEPEYELAISTALNKAAKNIIVDSNQDAINAVNFLKANKAGRATFLPLANLK
DRDVKPEHLEVLEQVEGYLGIAANLVNYHDQYDPAIRALLGQIIIASDLEAATKISKFTY
QLYRVISLGGDIVNAGGAITGGAESKQTHSLFNLDEKIDTLKNELLVTEKNINELNKKLE
LLTADYTKKDKEFNEQKIAIQRYQDLIVIEQKKLDDYKIQYEQLTDKTFDGKDVKWDDKK
IKDKLFSLETKKATLVQDLKINQEAKDMYQKQVNQLEKDVTLFYKEIDEDKNDKLKRREQ
LTKHENTIYLAKSKINEAYNMAIEFAIENYNKPLPISLSQARNEVVKLQSTLNNLGAINM
EAIQELDIKKERYEKLYSQQQELINARERINEAIIRLDEKAIFEFDQLINNLNKELPKTF
YYLFGGGNCEIRYSNPEEKLTSGIEVFASPPGKNIGNLNLLSGGEKALVALSVLFSILKV
SSFPLVVLDEAESALDLANVERFANIIKNSSDQTQFLIITHREGTMVKCDKLIGATMQTK
GVTKMLSVSLHQAKDMAEEIESQ