GCW_92264

Uniprot: A0A0F6CLZ2
Description: Bifunctional protein dihydrofolate reductase (DHFR) and ScpA/B segregation and condensation protein
EC number:
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): scpA
Gene names (synonym): scpB
Mass: 70,072
Subunit structure [CC]:
Gene ontology (GO): dihydrofolate reductase activity [GO:0004146]; NADP binding [GO:0050661]; glycine biosynthetic process [GO:0006545]; nucleotide biosynthetic process [GO:0009165]
Gene ontology IDs: GO:0004146; GO:0006545; GO:0009165; GO:0050661
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil: COILED 443 466 {ECO:0000256|SAM:Coils}.; COILED 500 528 {ECO:0000256|SAM:Coils}.
Domain [FT]: DOMAIN 1 155 DHFR (dihydrofolate reductase). {ECO:0000259|PROSITE:PS51330}.
Motif:
Region:
EMBL: CP006916
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: AHV85444
UniPathway: K05896
CDD:
Gene3D: cd00209
HAMAP: 3.40.430.10
InterPro:
PANTHER: IPR012259;IPR024072;IPR001796;IPR003768
PIRSF:
PRINTS:
PROSITE: PR00070
Pfam: PS51330
ProDom: PF00186;PF02616
SMART:
SUPFAM:
TIGRFAMs: SSF53597
530352-532125(-)

>nucleotide sequence
TTATTCTTCTTTAATTAGATCTTGTTCATCATCAAGTTTGATTAAACCAGTATGTAAAGC
TTCAAGTTTAGCTTGGGAATCATAGTCTTCTTGCTGATCATTAATCAGATCATCAAGTTG
TTTGATAATCAGATCAGCTTCATATAAGATCTGTTTGGCACTTGGTTTTTTAGTTTTTAG
ATCGATGATCTGATTATTTTCATCGACAAGGTTTTGGGCTTTAGCTTTATTAAGTTTTTC
TTGTTCATCAATCTTACGTTGGTTAATTCTGATATTAATCTTTTCTTCAGGTGTAAGCTT
TTGATATTGTTCACGTGAAACATAATATTCACCATATTTCTTCTTTAAATATTCTTCACG
TTGTTTAAAAAAGCTTTGCTTACGTTCTTCTTGGATCTGTTTGATCGATTCTTGTAAGGC
TTTTTCATCTTCTTGTTGACGTTGAATCACTTCTTGGATTGATTCTTGACTATTAACAAT
CTTAGTCGGATCAACTAAACAAGCAGAGATTGATTCATCATCGTTTTTTTGATTTAGATC
AATCTTTTGTTCACGCACTAAGATTAATAAACAAACAAAGCTTGTAACAAAGTACCGTAA
GCTTAATTTCTTGGGATCAATCTGTTCAAAGATCTTTTCTAGATCAATAAAACGATCATA
TTGATTATTTAATAATTTCCTGATAATTGATAAGATCTCATTTTTAACATCTTCGATTGA
TAACTCCTCGATCACGATCTTGTGTTCAGTGATCGTTTTAATCCTAAGCTTTTCAAAGAC
GCGCTCCATCGCCTTTTTTAACTTCTTGGGATTAACATAATCTGGTAATGGAGCTTCTAG
TAGATCATTACTAGTTAATTTGAAAACATCCCAATCATCTTCTTCTTTAGCAAACAGTGA
AAACCGTTCTAATTGCATCTTTTGTAATGATGGTAATAGTTCTGAATAACGTTTGTATTC
AATGATTCGTTTAACAATCCGATCACGCTCATCATCATTATTAAGATCGATCTTGGTCTC
ATCTTCAAAGTTGGGAATTGATAGATCAGATTTAATTCTTAACAGCTCACAAGCCATATA
TAAATAATCTGATACTAGATCAAGATTGATCATATGCTTATTGATATAAGCAAAATACTG
GTTGGTTAGTTCAAATAGATCTAATGCCATAATATCCATCTTCTTATCTTTAATCAGATG
AAGTAAGAGATCAAATGGCCCACTGAAGTGCTTAAATGATAGGTTTAAGAAATCATCATT
TAAGTTGATATTTAATTCTTCAATTAGATCTTCTGGTTTTTTGGTGTTTGGTTTACGTTC
TCAATACTCAACAACAAATTGATCGTATTCTTTAGTTTGCACCAAACTAAAGTCATCATA
ATTAAGATTAACAAAAAGATCACAACCATAATCAGCATTAAGTTTGGAGATCACTAATTG
ATCGGCATACTTAATTGCTTGTTCGATTGTTTTCTTACCCCCAATAATAAATAGATCAAC
AATACTAAAATCAATTAAGGCTTTCTTCAGATCTGAATATAAGAATAGTTCATTCTTATT
TTTTAATTCGTGCTGATGTTTTTTACTAATCACAATATTAGCTTGGTTAGCTAAGATCTT
GTTCATAGCAAGATAGGTATTATACCCCATGATGATCGGGTGATTGGTGGTAGTTTGGTG
GAAATGGTTTAGTTCCTCATCGATCCTTCAAGGGATTTGGTTGTTCTTAGCAATTCCATG
ATTAAGATCTTCACATCAGATAAGTTTGATCAT

>protein sequence
MIKLIWCEDLNHGIAKNNQIPWRIDEELNHFHQTTTNHPIIMGYNTYLAMNKILANQANI
VISKKHQHELKNKNELFLYSDLKKALIDFSIVDLFIIGGKKTIEQAIKYADQLVISKLNA
DYGCDLFVNLNYDDFSLVQTKEYDQFVVEYWERKPNTKKPEDLIEELNINLNDDFLNLSF
KHFSGPFDLLLHLIKDKKMDIMALDLFELTNQYFAYINKHMINLDLVSDYLYMACELLRI
KSDLSIPNFEDETKIDLNNDDERDRIVKRIIEYKRYSELLPSLQKMQLERFSLFAKEEDD
WDVFKLTSNDLLEAPLPDYVNPKKLKKAMERVFEKLRIKTITEHKIVIEELSIEDVKNEI
LSIIRKLLNNQYDRFIDLEKIFEQIDPKKLSLRYFVTSFVCLLILVREQKIDLNQKNDDE
SISACLVDPTKIVNSQESIQEVIQRQQEDEKALQESIKQIQEERKQSFFKQREEYLKKKY
GEYYVSREQYQKLTPEEKINIRINQRKIDEQEKLNKAKAQNLVDENNQIIDLKTKKPSAK
QILYEADLIIKQLDDLINDQQEDYDSQAKLEALHTGLIKLDDEQDLIKEE