GCW_92659







Uniprot: A0A0F6CM10
Description: S-adenosylmethionine synthetase
EC number: 
Annotation score: 1 out of 5
Miscellaneous [CC]: 
Protein existence: Inferred from homology
Catalytic activity: 
Cofactor: 
Enzyme regulation: 
Function [CC]: 
Pathway: 
Active site: 
Binding site: 
Calcium binding: 
DNA binding: 
Metal binding: 
Nucleotide binding: 
Site: 
Gene names (primary): 
Gene names (synonym): 
Mass: 41,627
Subunit structure [CC]: SUBUNIT: Homotetramer. {ECO:0000256|RuleBase:RU000542}.
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; metal ion binding [GO:0046872]; methionine adenosyltransferase activity [GO:0004478]; S-adenosylmethionine biosynthetic process [GO:0006556]
Gene ontology IDs: GO:0004478; GO:0005524; GO:0005737; GO:0006556; GO:0046872
Chain: 
Signal peptide: 
Domain [CC]: 
Sequence similarities: SIMILARITY: Belongs to the AdoMet synthase family. {ECO:0000256|RuleBase:RU004462}.
Protein families: AdoMet synthase family
Coiled coil: 
Domain [FT]: DOMAIN 1 88 S-AdoMet_synt_N. {ECO:0000259|Pfam:PF00438}.; DOMAIN 102 219 S-AdoMet_synt_M. {ECO:0000259|Pfam:PF02772}.; DOMAIN 222 355 S-AdoMet_synt_C. {ECO:0000259|Pfam:PF02773}.
Motif: 
Region: 
EMBL: CP006916
ProteinModelPortal: 
MEROPS: 
EnsemblBacteria KO: AHV85462
UniPathway: K00789
CDD: 
Gene3D: 
HAMAP: 
InterPro: 
PANTHER: IPR022631;IPR022630;IPR022629;IPR022628;IPR002133;IPR022636
PIRSF: PTHR11964
PRINTS: PIRSF000497
PROSITE: 
Pfam: PS00376;PS00377
ProDom: PF02773;PF02772;PF00438
SMART: 
SUPFAM: 
TIGRFAMs: SSF55973
627617-628742(-)

>nucleotide sequence
TTATTTTTTATTAACGATCTTTAAGATCTGATCAAGATAGATCGTATCTTCAAAACGGTA
TTGTTTTTCAGATTTACCAAAATGGCCATATACTGCTAAACCAGAATAATTTGTTGTTTT
AAGTTTTAATAGTTCAATAATTGTGGCTAGATCATGATTGAAAATCTTTTTAACGATCTG
ATTAATTAAATCAAGCTCTACAGTGTTCGTATTAAAACAATTAACAACGATATCAAGCGG
TTTGGTTAATCCGATCGCTCATGAGATGATCACTTCACATTGACTAGCAAGTTTGGCTTT
AACGATATGTTTAGCGATCCATCTTGCATAATAAGCACCCGAGCGATCCACTTTAGTGTA
ATCCTTACCACTATAAGCACCACCACCATGGTGAGCATAGATCCCAAAACTGTCTACTAA
CAGTTTTCTACCAGTCAAGCCCGTATCAGCAGTTGGACCACCACTAACAAACAATCCAGA
TGGATTGATTAATGCTTCGTAGTTTTTGTTAAAACCATATTTTGTGGCAACCTCATCCAT
AATGAATTTTTTAACAAAAAGTTTAAAAACACTTAGATCAACATTCTCTTCATGTTGGAT
TGACATTAAGATTGTTTTTAATTCAACTTGGTTATTCTCTAGATAATTCAAGCTCACTTG
AGCTTTCATATCATATTTAGCATGGTTAAAAGTTTTATTATCAATTAATTCTTTAGCTAA
ACGCACAAGATCGTGTGCCATCATTACGGCTAAAGGCATCTGATTTTTGGTTTCATCACA
AGCATAACCAACAGTGATCCCTTGATCACCAGCACCAATCTTGTGATTTTTTTGATCAAC
TGATTGGGCAATCTCAGATGATTGCTGATTAATATTTGCAATGATCGTAAAATCACTACG
ATCATAACCAAATTGGTTAACAACTTTTCAAGCTGTGCCAACATAATCAACACTAGCTTT
GGTACTAATCTCACCTGCAATAATAATTAGGTGATTACAAGCCATAACTTCACAAGCAAC
ACGGCTATTTTGATCTTGTTTTAAGCAAGCATCTAAGATCGCATCAGCGATCTGGTCACA
GATCTTATCAGGATGTGCACTACCAACACTTTCAGCAGTATACAC


>protein sequence
VYTAESVGSAHPDKICDQIADAILDACLKQDQNSRVACEVMACNHLIIIAGEISTKASVD
YVGTAWKVVNQFGYDRSDFTIIANINQQSSEIAQSVDQKNHKIGAGDQGITVGYACDETK
NQMPLAVMMAHDLVRLAKELIDNKTFNHAKYDMKAQVSLNYLENNQVELKTILMSIQHEE
NVDLSVFKLFVKKFIMDEVATKYGFNKNYEALINPSGLFVSGGPTADTGLTGRKLLVDSF
GIYAHHGGGAYSGKDYTKVDRSGAYYARWIAKHIVKAKLASQCEVIISWAIGLTKPLDIV
VNCFNTNTVELDLINQIVKKIFNHDLATIIELLKLKTTNYSGLAVYGHFGKSEKQYRFED
TIYLDQILKIVNKK






















© Fisunov Lab of Proteomics, 2016.