SPM_000125

Uniprot: A0A037US30
Description: cytidine deaminase
EC number:
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Predicted
Catalytic activity:
Cofactor: COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000256|PIRSR:PIRSR006019-2};
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 85 85 Proton donor. {ECO:0000256|PIRSR:PIRSR006019-1}.
Binding site:
Calcium binding:
DNA binding:
Metal binding: METAL 83 83 Zinc; catalytic. {ECO:0000256|PIRSR:PIRSR006019-2}.; METAL 108 108 Zinc; catalytic. {ECO:0000256|PIRSR:PIRSR006019-2}.; METAL 111 111 Zinc; catalytic. {ECO:0000256|PIRSR:PIRSR006019-2}.
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 18,990
Subunit structure [CC]:
Gene ontology (GO): dCMP deaminase activity [GO:0004132]; zinc ion binding [GO:0008270]; pyrimidine nucleotide metabolic process [GO:0006220]
Gene ontology IDs: GO:0004132; GO:0006220; GO:0008270
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities:
Protein families:
Coiled coil:
Domain [FT]: DOMAIN 14 143 CMP/dCMP-type deaminase. {ECO:0000259|PROSITE:PS51747}.
Motif:
Region:
EMBL: AGBZ02000001
ProteinModelPortal: A0A037US30
MEROPS:
EnsemblBacteria KO: KAI92525
UniPathway:
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR016192;IPR002125;IPR016193;IPR016473;IPR015517
PIRSF: PTHR11086
PRINTS: PIRSF006019
PROSITE:
Pfam: PS00903;PS51747
ProDom: PF00383
SMART:
SUPFAM:
TIGRFAMs: SSF53927

20813-21314(-)

>nucleotide sequence
TTATTTTTCCTTTTGTCGTTCTACTATAACATTAATAATTGGTAAACAACGATAACGAAC
TTGTGCTTGGTCAAACATCCGTTTTGCTGCTTGATTATCATCGCTACCTTCGTATTTGTC
ATCATCATAAATAACTTCTTTAATTCCAGCTTGAATAATAATTTTTGTACATTCTGCACA
AGGAAATAAAGTTGTATAAATCCGACAGTTTTCTAAATTTGTTCGTGCACTTAAAATGGC
ATTCAATTCAGCATGCGCAACATAAGGATATTTTGTTTCTAAATATTTCCCTTCTCGCGC
TCATGGAAAATCATCATCATTTAAGCCACGGGGTAAACCATTATAACCTGTCGCAATAAT
TTGTCCAATTTGATTAACAACACAACTGCCAACTTGGGTATGGGGGTCTTTGCTTCGCAT
TGCACAAACATGCGCAACGCTTAAGAAGAAATCATCTCATGATAAATAATCATTACGTTT
TTTCTCTGCTACTGTTGTCAT

>protein sequence
MTTVAEKKRNDYLSWDDFFLSVAHVCAMRSKDPHTQVGSCVVNQIGQIIATGYNGLPRGL
NDDDFPWAREGKYLETKYPYVAHAELNAILSARTNLENCRIYTTLFPCAECTKIIIQAGI
KEVIYDDDKYEGSDDNQAAKRMFDQAQVRYRCLPIINVIVERQKEK