SPM_000165

Uniprot: A0A037UPJ1
Description: cell division protein FtsZ
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. {ECO:0000256|HAMAP-Rule:MF_00909, ECO:0000256|RuleBase:RU000631}.
Pathway:
Active site:
Binding site: BINDING 138 138 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.; BINDING 142 142 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.; BINDING 185 185 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 20 24 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.; NP_BIND 107 109 GTP. {ECO:0000256|HAMAP-Rule:MF_00909}.
Site:
Gene names (primary): ftsZ
Gene names (synonym):
Mass: 44,130
Subunit structure [CC]:
Gene ontology (GO): cell division site [GO:0032153]; cytoplasm [GO:0005737]; GTP binding [GO:0005525]; GTPase activity [GO:0003924]; FtsZ-dependent cytokinesis [GO:0043093]; protein polymerization [GO:0051258]
Gene ontology IDs: GO:0003924; GO:0005525; GO:0005737; GO:0032153; GO:0043093; GO:0051258
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the FtsZ family. {ECO:0000256|HAMAP-Rule:MF_00909, ECO:0000256|RuleBase:RU000631}.
Protein families: FtsZ family
Coiled coil:
Domain [FT]: DOMAIN 12 203 Tubulin. {ECO:0000259|SMART:SM00864}.; DOMAIN 205 322 Tubulin_C. {ECO:0000259|SMART:SM00865}.
Motif:
Region:
EMBL: AGBZ02000001
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92533
UniPathway:
CDD:
Gene3D:
HAMAP: 3.30.1330.20;3.40.50.1440
InterPro: MF_00909
PANTHER: IPR000158;IPR020805;IPR024757;IPR008280;IPR018316;IPR003008
PIRSF:
PRINTS:
PROSITE: PR00423
Pfam: PS01135
ProDom: PF12327;PF00091
SMART:
SUPFAM: SM00864;SM00865
TIGRFAMs: SSF52490;SSF55307

28774-30010(-)

>nucleotide sequence
TTATCAACTACGACGAACAAATGGTGGTAAATCATCATCTTCATCGTCATGTTCAACTAC
TTGATTATTATTAACATGCTCTCGTCACGCATTAATTCGACGGTTTGCATTTGCTGTTTC
ACGTTCAGAATTTTCTGATAAATTAGTGAAATAACTTGGTCGTTTACGAGCAATATCTTG
ATCATTGTTGTCATCATTAATCTCAGCGTCACGAGTTGGACGCGGTGCTGGTGCTTCATA
TTCTTCCATTGAAGCACGATAAGTATTATCCGGATTAGTAAAATTTTGTTCTTCATCAAA
CCCAGTCGCAATTACAGTTACAATCATTTCATCATCTAAATGCTCATTAACTGCTGTTCC
AAAAATAATATTAACTTCGCCGCCAATTGCTTGTTTAACAATATCAACAGCGTCATTAGC
ATCATTTAAGGTTAAGGTATTTCCACCAGTAACATTAATAATAGCATCACGTGCACCACG
GATCGACGCTTCTAATAATGGAGAAATAATTGCTTTATTAGCAGCTTCAATTGCTTTATC
TTTACCTGAACCAATACCGATCCCAAATAAAGCGTTCCCTTTATTTTTCATAACAGTCTT
AATATCTGCAAAGTCTAAATTAATTAAGGATGGTACTGCAATTAAATCAGTAATGGTTTG
AACTCCTTGGCGTAAAATATTATCGGCTTCTTTGAACGAATCTTTTAATGGGACACCCCC
AATGACTTCTAATAAGCGATCATTTGAAATAATAATTAATGAATCAACATGCTTACGTAG
TTCTTCCGTTCCTTGGATGGCATAACTATTGCGCGCACGACCTTCAAATGAAAATGGCGT
TGTAATAATTCCAACGGTTAAAGCGCCTTGTTCTCTAGCAAGTTTGGCAATAATAGGAGC
AGCCCCAGTTCCAGTTCCACCACCCATTCCAGCGGCAACAAAAACCATATCTGCCCCTTT
TAAAGCATCTTTAATTTCTTCTGCTGATTCAATTGCTGCTTGGCGACCAACATCAGGATT
AGCACCTGCTCCTAGCCCCTTCGATGTTTCTTTACCCAATACAATTTTATTTTTTGACTT
TGAAACACTAATAATCTGGGCATCAGTATTAGCAACAATAAATTCAACCCCTTGCACGCC
TGCTTCAATCATACGATTAACTGCATTATTACCAGCACCACCAATACCGATCACTTTTAT
TGACGCGACTTGTTCATAATTATCAAAATTGTCCAT

>protein sequence
MDNFDNYEQVASIKVIGIGGAGNNAVNRMIEAGVQGVEFIVANTDAQIISVSKSKNKIVL
GKETSKGLGAGANPDVGRQAAIESAEEIKDALKGADMVFVAAGMGGGTGTGAAPIIAKLA
REQGALTVGIITTPFSFEGRARNSYAIQGTEELRKHVDSLIIISNDRLLEVIGGVPLKDS
FKEADNILRQGVQTITDLIAVPSLINLDFADIKTVMKNKGNALFGIGIGSGKDKAIEAAN
KAIISPLLEASIRGARDAIINVTGGNTLTLNDANDAVDIVKQAIGGEVNIIFGTAVNEHL
DDEMIVTVIATGFDEEQNFTNPDNTYRASMEEYEAPAPRPTRDAEINDDNNDQDIARKRP
SYFTNLSENSERETANANRRINAWREHVNNNQVVEHDDEDDDLPPFVRRSW