SPM_001050

Uniprot: A0A037UPZ0
Description: ribulose-phosphate 3-epimerase
EC number: 5.1.3.1
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: D-ribulose 5-phosphate = D-xylulose 5-phosphate. {ECO:0000256|PIRNR:PIRNR001461}.
Cofactor: COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000256|PIRSR:PIRSR001461-2}; ; Note=Binds 1 divalent metal cation per subunit. {ECO:0000256|PIRSR:PIRSR001461-2}
Enzyme regulation:
Function [CC]:
Pathway:
Active site: ACT_SITE 36 36 Proton acceptor. {ECO:0000256|PIRSR:PIRSR001461-1}.; ACT_SITE 182 182 Proton donor. {ECO:0000256|PIRSR:PIRSR001461-1}.
Binding site: BINDING 9 9 Substrate. {ECO:0000256|PIRSR:PIRSR001461-3}.; BINDING 67 67 Substrate. {ECO:0000256|PIRSR:PIRSR001461-3}.; BINDING 184 184 Substrate; via amide nitrogen. {ECO:0000256|PIRSR:PIRSR001461-3}.
Calcium binding:
DNA binding:
Metal binding: METAL 34 34 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.; METAL 36 36 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.; METAL 67 67 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.; METAL 182 182 Divalent metal cation. {ECO:0000256|PIRSR:PIRSR001461-2}.
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 24,754
Subunit structure [CC]:
Gene ontology (GO): metal ion binding [GO:0046872]; ribulose-phosphate 3-epimerase activity [GO:0004750]; carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]
Gene ontology IDs: GO:0004750; GO:0005975; GO:0006098; GO:0046872
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribulose-phosphate 3-epimerase family. {ECO:0000256|PIRNR:PIRNR001461}.
Protein families: Ribulose-phosphate 3-epimerase family
Coiled coil:
Domain [FT]:
Motif:
Region: REGION 149 152 Substrate binding. {ECO:0000256|PIRSR:PIRSR001461-3}.; REGION 204 205 Substrate binding. {ECO:0000256|PIRSR:PIRSR001461-3}.
EMBL: AGBZ02000001
ProteinModelPortal: A0A037UPZ0
MEROPS:
EnsemblBacteria KO: KAI92658
UniPathway:
CDD:
Gene3D: cd00429
HAMAP: 3.20.20.70
InterPro:
PANTHER: IPR013785;IPR026019;IPR000056;IPR011060
PIRSF: PTHR11749
PRINTS: PIRSF001461
PROSITE:
Pfam: PS01085;PS01086
ProDom: PF00834
SMART:
SUPFAM:
TIGRFAMs: SSF51366

186849-187530(-)

>nucleotide sequence
TTATTTGTTTTCATTTGCTAATAATCCTTTCAACCGGGTTGCTAAATCTGCATGACCAAA
TAAATAACTACCCGCTACTAATACATCAACCCCATATTGTTTACAAAGAGTTGCAGTCTC
AGCATTAATTCCTCCGTCAACTTCAATTAATGTTTTGCCATTATTTTGATCAAGATAGTC
TCGTAAGGCTTTAATCTTTGTTGCTGCAGCTGAAATAAAAGTTTGACCGCCAAAACCAGG
TTCTACTGTCATTACTAAGACTAAATCAAGATGTTTTAAATAAGGGAAAATAACTTTAAC
TGGGGTTGCTGGTTTAATTGCTAACCCAATTTTTATGTTTAATTTTATTCGTAAATTTAA
AAATTCAGTTAATTGTGGTGGGGTTAATGCTTCATAATGCAAAGTAATTGCTGATGCACC
CGCTTTAATAAAAGGCAGCAAATAATTTTCAACACTACTATTTTTAATTTTAACCATTAA
GTGACAATCAAGATACAAATCACTATAACTAGTAATATCAGCTAAAATCTTTGGACCAAA
AGTTAAATTTGGTACAAAATCACCATCCATTACATCAAAATGAATTCATTGTGCGCCAGC
TTCCTTAATTGCTGCTAATTCTTCTTGTAAGATTAAATAATTTGCACTTAAAACACTTGG
TGCAACAAGATATTTTTTCAT

>protein sequence
MKKYLVAPSVLSANYLILQEELAAIKEAGAQWIHFDVMDGDFVPNLTFGPKILADITSYS
DLYLDCHLMVKIKNSSVENYLLPFIKAGASAITLHYEALTPPQLTEFLNLRIKLNIKIGL
AIKPATPVKVIFPYLKHLDLVLVMTVEPGFGGQTFISAAATKIKALRDYLDQNNGKTLIE
VDGGINAETATLCKQYGVDVLVAGSYLFGHADLATRLKGLLANENK