SPM_001915

Uniprot: A0A037UT54
Description: glutamyl-tRNA amidotransferase
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate. {ECO:0000256|SAAS:SAAS00573105}.; CATALYTIC ACTIVITY: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. {ECO:0000256|SAAS:SAAS00512389}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln). {ECO:0000256|SAAS:SAAS00573109}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 11,197
Subunit structure [CC]: SUBUNIT: Heterotrimer of A, B and C subunits. {ECO:0000256|SAAS:SAAS00573103}.
Gene ontology (GO): ATP binding [GO:0005524]; ligase activity [GO:0016874]; transferase activity [GO:0016740]; regulation of translational fidelity [GO:0006450]; translation [GO:0006412]
Gene ontology IDs: GO:0005524; GO:0006412; GO:0006450; GO:0016740; GO:0016874
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the GatC family. {ECO:0000256|SAAS:SAAS00573107}.
Protein families: GatC family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: AGBZ02000001
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92790
UniPathway:
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR003837
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF02686
SMART:
SUPFAM:
TIGRFAMs: SSF141000

349435-349729(-)

>nucleotide sequence
TTATTTAACCACCTTATTAATTACAATATAATCATCTATTTTTTTTGGTGCTGCCGCTAA
AATTTCAGCTTGTGGAGCAACATCAATTTCATCATCCTCACGCAAATAGTCAACTGTTAA
GTCAAATGGAAAATGCATTGAATGAACATTAGTTGTATTAATTTTTTGTACTAAATCCAT
TTGCTTTAAAATAACATCAAATTCTTGACTTAAATTAGTTAGTTCCTCATCTTGTAAATC
TAGCATAATATCATGTGCTAACATCTGTAGCACTTCTTTTGTAATTCGTGCCAT

>protein sequence
MARITKEVLQMLAHDIMLDLQDEELTNLSQEFDVILKQMDLVQKINTTNVHSMHFPFDLT
VDYLREDDEIDVAPQAEILAAAPKKIDDYIVINKVVK