SPM_002040

Uniprot: A0A037UN74
Description: lactate dehydrogenase
EC number:
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 37,600
Subunit structure [CC]:
Gene ontology (GO): NAD binding [GO:0051287]; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [GO:0016616]
Gene ontology IDs: GO:0016616; GO:0051287
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
Protein families: D-isomer specific 2-hydroxyacid dehydrogenase family
Coiled coil:
Domain [FT]: DOMAIN 8 329 2-Hacid_dh. {ECO:0000259|Pfam:PF00389}.; DOMAIN 115 299 2-Hacid_dh_C. {ECO:0000259|Pfam:PF02826}.
Motif:
Region:
EMBL: AGBZ02000001
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92807
UniPathway:
CDD:
Gene3D:
HAMAP: 3.40.50.720
InterPro:
PANTHER: IPR006139;IPR029753;IPR029752;IPR006140;IPR016040
PIRSF:
PRINTS:
PROSITE:
Pfam: PS00065;PS00671
ProDom: PF00389;PF02826
SMART:
SUPFAM:
TIGRFAMs: SSF51735

364763-365756(-)

>nucleotide sequence
TTATATTTTATTTTTTGATTCACCATTTGCTAAAATTTCTTTTAAATTTTCATATGTTGT
TTCAATCATATTTTTGACAGCTTCATCAGTATAAGATCCTATATGCGGTGTAATAATTAC
TCGTGGATATAAGGTAAGTAATTTATTTGTAATATTATCTGGTGTTATATTTTCATTAAA
ATCTTGAAAAAAAACATCACCTTCATTTTCTAATACATCTAACCCAACACCTTTTAAGTG
ATTTGACTTAATAGCTTCATAAACTGCCTCACTATCCATTAGTTGTCCACGCGCTGCATT
AATTAACACTGACCCTGGTTTCATTTGTGCTAGAAATTCTTTATTAACAAAATGATGATT
TTGTTCTTTAATATATGGACAATGTAATGAAACTAAGTCTGATTCTTTAAGCAAAGTATT
TAAATCAGTATATGTTAAAACTGTTCGAACACTATCGTTTTCATAAATATCGTATCCTAA
TACTTTAGCTCCCATTCCGTGTCAAGCTTTTGCTGCTTCAAAACCAATTCGACCAGTTCC
AATAATTCCAATTGTAGAATTACGAATTTCTTTTGCAAACATAAAATCATCAACTTTAAA
ATTTGTTTTACGTTCATTATTAGCCATATAAAATAAATTACGTAAAAAAGCATTTCCCAT
TGCTACCGCTAATTCGCTAACTGCATTAGGCGAATATCCTGGAACATAAGCCATTTTAAA
CCCTAATTCATGTGCTTTTGTTAAGTCAATATGATTATAACCAACTGTTCTTGTTAATAA
ATATTTAACGCCATATTCTTGCATTTTTAATAAGTTTTCTTCATAACAGTCACAATTTGC
ACGAACCATTACTGCTTGATGTCCTTTAACTGTTTCAATATTATCTTTTGTTAAATATTC
TTCAATTAAAGTTAAATCATAACCATATTTTTCATTTAGTTTTTCAAAAAATGGTCGTTC
GGTTTTCCGAACGCCATAACAAACCATTTTAAT

>protein sequence
IKMVCYGVRKTERPFFEKLNEKYGYDLTLIEEYLTKDNIETVKGHQAVMVRANCDCYEEN
LLKMQEYGVKYLLTRTVGYNHIDLTKAHELGFKMAYVPGYSPNAVSELAVAMGNAFLRNL
FYMANNERKTNFKVDDFMFAKEIRNSTIGIIGTGRIGFEAAKAWHGMGAKVLGYDIYEND
SVRTVLTYTDLNTLLKESDLVSLHCPYIKEQNHHFVNKEFLAQMKPGSVLINAARGQLMD
SEAVYEAIKSNHLKGVGLDVLENEGDVFFQDFNENITPDNITNKLLTLYPRVIITPHIGS
YTDEAVKNMIETTYENLKEILANGESKNKI