SPM_002265

Uniprot: A0A037UQL4
Description: 50S ribosomal protein L7/L12
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. {ECO:0000256|HAMAP-Rule:MF_00368}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rplL
Gene names (synonym):
Mass: 12,472
Subunit structure [CC]: SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. {ECO:0000256|HAMAP-Rule:MF_00368}.
Gene ontology (GO): ribosome [GO:0005840]; structural constituent of ribosome [GO:0003735]; translation [GO:0006412]
Gene ontology IDs: GO:0003735; GO:0005840; GO:0006412
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L7/L12P family. {ECO:0000256|HAMAP-Rule:MF_00368}.
Protein families: Ribosomal protein L7/L12P family
Coiled coil:
Domain [FT]: DOMAIN 5 50 Ribosomal_L12_N. {ECO:0000259|Pfam:PF16320}.; DOMAIN 56 121 Ribosomal_L12. {ECO:0000259|Pfam:PF00542}.
Motif:
Region:
EMBL: AGBZ02000001
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92848
UniPathway:
CDD:
Gene3D:
HAMAP: 3.30.1390.10
InterPro: MF_00368
PANTHER: IPR000206;IPR014719;IPR013823;IPR008932
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF00542;PF16320
SMART: PD001326
SUPFAM:
TIGRFAMs: SSF48300;SSF54736

420404-420770(-)

>nucleotide sequence
TTATTTAAGATCAACTGAAGCTCCAGCTGCTACTAATTGTCCTTTAATTTCTTCTGCTTC
TTCTACTTTTACTTTTTCTTTAATTACTGCTGGTAATTTATCAACAATCGCTTTTGCTGC
CATTAATTCTTTTCCAGTAATTTCTTTAACTAATTTAATAATTGCAACTTTACTTGGTCC
TGTATCTGTTAACACAATATTAACCTCTGAAGGCCCCGCTGCTGCTGATCCTTCTGCTGG
AGCTGCGGCAACTGCTGCGGCAGCTACAACACCAAAATGATCTTCAATTGCTTTTACTAA
TTCATTTAAATCTGATAATTTCATTTCTTCTAATGCTTTAATAATATCATCTTTTGATAA
TGCCAT

>protein sequence
MALSKDDIIKALEEMKLSDLNELVKAIEDHFGVVAAAAVAAAPAEGSAAAGPSEVNIVLT
DTGPSKVAIIKLVKEITGKELMAAKAIVDKLPAVIKEKVKVEEAEEIKGQLVAAGASVDL
K