SPM_002650

Uniprot: A0A037UM45
Description: peptide chain release factor 1
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. {ECO:0000256|HAMAP-Rule:MF_00093}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): prfA
Gene names (synonym):
Mass: 40,810
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; translation release factor activity, codon specific [GO:0016149]
Gene ontology IDs: GO:0005737; GO:0016149
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the prokaryotic/mitochondrial release factor family. {ECO:0000256|HAMAP-Rule:MF_00093}.
Protein families: Prokaryotic/mitochondrial release factor family
Coiled coil:
Domain [FT]: DOMAIN 230 246 RF_PROK_I. {ECO:0000259|PROSITE:PS00745}.
Motif:
Region:
EMBL: AGBZ02000001
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92914
UniPathway:
CDD:
Gene3D:
HAMAP: 3.30.160.20
InterPro: MF_00093
PANTHER: IPR014720;IPR005139;IPR000352;IPR004373
PIRSF:
PRINTS:
PROSITE:
Pfam: PS00745
ProDom: PF03462;PF00472
SMART:
SUPFAM: SM00937
TIGRFAMs:

502877-503954(+)

>nucleotide sequence
ATGAATCAAAAAACAATTGAACGATTAGAAACGATGTTAAAGCGGTGAAATTTAATTAAT
GAAGAATTAACGAAACCAGAAATAGTTAATGATGTAAAAAAATTAACTAGTTTAGCAAAA
GAACAAGCACAATTAGAGGAAACCGTTGCTTTATACTTAAATTATAAAAATGTTTTAAAT
AATATTAATGAAGCAAAATTAATTTTAGAGACAGAAAAAGATTATGAATTAATTGAATTA
GCAAAAGAAGAATTAAAAACTTCGGAAATAAGAAAAGAACAACTTGCAGCAGAATTAAAG
GTAATATTATTACCAAAAGATCCTAATGATGATAAAAATGTTATTTTTGAAATTCGTGGA
GCAGCGGGTGGTGATGAAGGAAATATTTTTGCTGGTGATTTATATCGAATGTATATAAAA
TATGCAGAGCAACAACATTGAAAAGTAGAATTAATTGAAGCAAATGAATCAGAAGCAGGA
GGTTTTTCTACAATTTCGTTTATGGTTAAAGGAGATCGTGTTTATTCAAAAATGAAATTT
GAATCAGGGGCACATCGTGTTCAACGAATTCCAAAAACAGAAAGTAAAGGTCGAGTACAT
ACATCAACTGCAACCGTTGCTGTTTTACCAGAAATTGAAGAAGTTGATTTTGAAATTAAA
ACTGCTGATTTAAAAATTGATACTTACCGTGCTTCAGGAGCAGGGGGACAACATGTTAAT
ACAACTGATTCAGCTGTTCGAATTACGCATTTACCAACGGGGGTTGTTGTAACTTCCCAA
GATGGTCGTAGTCAACATGATAATAAAGCATTAGCAATGCAACATTTACGAAGTAAGTTA
TATGAAGAACAACAACGTAAAATTAATGAAGAACGTGGAACATTAAGAAAAGATGCAGTA
GGAACAGGTGACCGGAGCGAAAAGATTCGAACATATAATTATCCTCAGAATCGGGTTACC
GATCATCTTATTAATTTAACACTACAAAAATTAGACCAAATTATGGAAGGTAATTTAGAC
GAAATTGTAGTAGCATTAATTAATGAAGAACAGAGATTGAAAATGGAAGGAAACTAA

>protein sequence
MNQKTIERLETMLKRWNLINEELTKPEIVNDVKKLTSLAKEQAQLEETVALYLNYKNVLN
NINEAKLILETEKDYELIELAKEELKTSEIRKEQLAAELKVILLPKDPNDDKNVIFEIRG
AAGGDEGNIFAGDLYRMYIKYAEQQHWKVELIEANESEAGGFSTISFMVKGDRVYSKMKF
ESGAHRVQRIPKTESKGRVHTSTATVAVLPEIEEVDFEIKTADLKIDTYRASGAGGQHVN
TTDSAVRITHLPTGVVVTSQDGRSQHDNKALAMQHLRSKLYEEQQRKINEERGTLRKDAV
GTGDRSEKIRTYNYPQNRVTDHLINLTLQKLDQIMEGNLDEIVVALINEEQRLKMEGN