SPM_003455

Uniprot: A0A037UR61
Description: rRNA maturation factor
EC number: 3.1.-.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor: COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000256|HAMAP-Rule:MF_00009}; ; Note=Binds 1 zinc ion. {ECO:0000256|HAMAP-Rule:MF_00009}
Enzyme regulation:
Function [CC]: FUNCTION: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_00009, ECO:0000256|SAAS:SAAS00023212}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding: METAL 120 120 Zinc; catalytic. {ECO:0000256|HAMAP-Rule:MF_00009}.; METAL 124 124 Zinc; catalytic. {ECO:0000256|HAMAP-Rule:MF_00009}.; METAL 130 130 Zinc; catalytic. {ECO:0000256|HAMAP-Rule:MF_00009}.
Nucleotide binding:
Site:
Gene names (primary): ybeY
Gene names (synonym):
Mass: 18,601
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; endoribonuclease activity [GO:0004521]; metalloendopeptidase activity [GO:0004222]; zinc ion binding [GO:0008270]; rRNA processing [GO:0006364]
Gene ontology IDs: GO:0004222; GO:0004521; GO:0005737; GO:0006364; GO:0008270
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the endoribonuclease YbeY family. {ECO:0000256|HAMAP-Rule:MF_00009, ECO:0000256|SAAS:SAAS00543484}.
Protein families: Endoribonuclease YbeY family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: AGBZ02000001
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI93033
UniPathway:
CDD:
Gene3D:
HAMAP: 3.40.390.30
InterPro: MF_00009
PANTHER: IPR023091;IPR002036;IPR020549
PIRSF:
PRINTS:
PROSITE:
Pfam: PS01306
ProDom: PF02130
SMART:
SUPFAM:
TIGRFAMs:

650790-651267(+)

>nucleotide sequence
ATGAAAGACGATTTTGTGATTTACAATGAAACAGATTTTGATATTAAACCATATCAAGAT
GATTTTAATGCAATTTTTCAAAAAATTAAAACTTTGTTAGCAATAACTGAACCATTAGAA
TTATCATTAATTATTGTTGATGCACAAGAACAACTAGAACTTAATCAAAAATATCGTCAC
AAAGATTATGTAGCTGATGTTATTACCTTTGCTTTAGAAGAAGAAAATAAGATTGATTTA
TTTGAGCTAACTGGATTACGCAGTCTAGGTGATATTTTTATTTGTTATGAAAAAGCACTT
GCTCAAGCTGCTGAATATAATCATTCTCCTCGGCGTGAATTTGCTTTTTTATTTACCCAT
GGGATGTTACATATTTTAGGTTATGATCATCAAACTCCAGCTGATGAAGAGAAAATGTTT
AATTTACAACGAAAAGTATTAAATGATTTACAAATTAACCGAATTCCAATAAAATAA

>protein sequence
MKDDFVIYNETDFDIKPYQDDFNAIFQKIKTLLAITEPLELSLIIVDAQEQLELNQKYRH
KDYVADVITFALEEENKIDLFELTGLRSLGDIFICYEKALAQAAEYNHSPRREFAFLFTH
GMLHILGYDHQTPADEEKMFNLQRKVLNDLQINRIPIK