SPM_003955

Uniprot: A0A037UKK7
Description: cytosine methyltransferase
EC number: 2.1.1.37
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. {ECO:0000256|RuleBase:RU000417}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 46,866
Subunit structure [CC]:
Gene ontology (GO): DNA (cytosine-5-)-methyltransferase activity [GO:0003886]; DNA restriction-modification system [GO:0009307]
Gene ontology IDs: GO:0003886; GO:0009307
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. {ECO:0000256|RuleBase:RU000416}.
Protein families: Class I-like SAM-binding methyltransferase superfamily, C5-methyltransferase family
Coiled coil:
Domain [FT]: DOMAIN 4 391 SAM-dependent_MTases. {ECO:0000259|Pfam:PF00145}.
Motif:
Region:
EMBL: AGBZ02000002
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92464
UniPathway:
CDD:
Gene3D:
HAMAP: 3.40.50.150
InterPro:
PANTHER: IPR018117;IPR001525;IPR029063
PIRSF:
PRINTS:
PROSITE: PR00105
Pfam: PS00094;PS51679
ProDom: PF00145
SMART:
SUPFAM:
TIGRFAMs: SSF53335

6656-7871(-)

>nucleotide sequence
TTAACTTGCTCCACTAACACTTTTTTCATAAAAACTTAATAATCCTTTCAAAACCACTTC
TGCTATATTAATAGTTATTGTATTTCCTAATTGTTTCATTGAAATATTATCATTTTTTGC
TAATTTAAATTCTTTGGGAAATCCCTGAATTAGTTTAACTTCTTCTGGAGTAATATATCT
TTTATATTTTCCTATTATTTGCGCATGATTCATAGCTACTAAAGTAGATAAAATATCTGC
TTTTTTAACTCTTATCCCAGATGGTCTAAACTGAATCATACCATTTCAAATTGAATTAAT
GGATTCCCCAGCTTGTCATTCAAATTTTTTATGTGCTATGTTAGTTACTCAATTTAAATT
ATCATTTTCTTTAAGTCATTTATCAATAAAATTTTTATTTCTTTTATATAAATCCAAATT
TTTTGATATTATTCTTCATTTTCAATCTGGAAAATATTCCTTATTACTTTCATAATTTCT
ATTATTTATAAAAATATCTGCTCAAATTGGAAATCCAATAATTTTAATATCAATATTATT
ATAAAATTCATTTCATAAATTTAATAAGTTTATTTCATAATCATTTAAATAATATTTATT
ATTTAAATCTTTACTTGATAAAAATGATCAGATATCTTGTGAAACTTTTGTTTCTTTAAC
CTCTTTCATAATACTATTAAACATTTCAATTCCATTTGAATTGCTTAAATCTTTTCTAAT
CCCTGGAATATAAATTCTTTTTCTATGCATTGGTATTCCAATATCCGTAGGAGTCAATAC
TAATGGTTTGGAAGGAAAAATATAGCCTAATCTTGTTAATTCTTCTGTTATAACTCTATA
TGTATTACCATTATCATGACTAACTAAATTACTAACATTTTCAAGTAAAAGAAAAATTGG
TTTTTTTGCTTGCAAAATTCTAACTATTTCAAAAAATAAGGCTCCTCTTGTATCATTAAA
TCCTTTTTGAAAGCCCCCTTTTGAAAACGGTTGACATGGAAAACCAGCACATAATAAATC
AAAATCAGGGATTGTATTTTCATCTATTTCTTTAATATCGCCTAAAATCTTATTATTAAA
ATTATTTAAATAAACTTCTCTACAATACTGATCTATATCACATGCAAATATTAATTCTGA
GTTTGAGATTTTATTCAAAGCTAAATGAAAGCCTCCTATACCAGCAAACAAATCTACAAA
TTTTATTTTTTCCAT

>protein sequence
MEKIKFVDLFAGIGGFHLALNKISNSELIFACDIDQYCREVYLNNFNNKILGDIKEIDEN
TIPDFDLLCAGFPCQPFSKGGFQKGFNDTRGALFFEIVRILQAKKPIFLLLENVSNLVSH
DNGNTYRVITEELTRLGYIFPSKPLVLTPTDIGIPMHRKRIYIPGIRKDLSNSNGIEMFN
SIMKEVKETKVSQDIWSFLSSKDLNNKYYLNDYEINLLNLWNEFYNNIDIKIIGFPIWAD
IFINNRNYESNKEYFPDWKWRIISKNLDLYKRNKNFIDKWLKENDNLNWVTNIAHKKFEW
QAGESINSIWNGMIQFRPSGIRVKKADILSTLVAMNHAQIIGKYKRYITPEEVKLIQGFP
KEFKLAKNDNISMKQLGNTITINIAEVVLKGLLSFYEKSVSGAS