SPM_004715

Uniprot: A0A037UKL7
Description: 16S rRNA methyltransferase
EC number: 2.1.1.-
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: Specifically methylates the N7 position of a guanine in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_00074}.
Pathway:
Active site:
Binding site: BINDING 74 74 S-adenosyl-L-methionine; via carbonyl oxygen. {ECO:0000256|HAMAP-Rule:MF_00074}.; BINDING 79 79 S-adenosyl-L-methionine; via carbonyl oxygen. {ECO:0000256|HAMAP-Rule:MF_00074}.; BINDING 142 142 S-adenosyl-L-methionine. {ECO:0000256|HAMAP-Rule:MF_00074}.
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rsmG
Gene names (synonym):
Mass: 26,567
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; rRNA (guanine-N7-)-methyltransferase activity [GO:0070043]
Gene ontology IDs: GO:0005737; GO:0070043
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. {ECO:0000256|HAMAP-Rule:MF_00074, ECO:0000256|SAAS:SAAS00573635}.
Protein families: Methyltransferase superfamily, RNA methyltransferase RsmG family
Coiled coil:
Domain [FT]:
Motif:
Region: REGION 125 126 S-adenosyl-L-methionine binding. {ECO:0000256|HAMAP-Rule:MF_00074}.
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92042
UniPathway:
CDD:
Gene3D:
HAMAP: 3.40.50.150
InterPro: MF_00074
PANTHER: IPR003682;IPR029063
PIRSF:
PRINTS: PIRSF003078
PROSITE:
Pfam:
ProDom: PF02527
SMART:
SUPFAM:
TIGRFAMs: SSF53335

12214-12913(+)

>nucleotide sequence
ATGATTAAATTAATTAAAACAGCTTTACCAGCATTACAAATTACACCTGAACAAGAAAAA
CAGTTACAAGTATATTATCAATATTTAATTGAACAAAACCAAATTATGAATTTAACCACA
ATTATTAAGGAAGAAGAGGTTTATCTTAAACATTTTCTTGATTCAGGATTATTATTAAAA
GAATTCTCATTTTCTAAGGAGATGACAGTTAGTGATGTTGGTAGTGGGGCTGGTTTTCCA
GGGCTTGTTTTAAAAATTCTTTGTCCAACAATTAAATTAACAATTATTGAATCGTTAGAA
AAACGATGTTTATTTTTACAACGATTAGTGCTGAAGTTACAGTTAAAAGATGTTGAAATT
ATTCATGCTCGAGCAGAAGAATATAGTTGAGCGCATTCTGAATCTTTTGATATTGTTGTT
TCTCGTGCTGTTGCTAATTTAGGTATGCTATTAGAATTGGTAGTGCGAATGGTTAAAACA
TCAGGAATGATTATTTGTTATAAAGGACCAAATGTTAATGCTGAATTGCAGGCAGCGCAA
AAAACTTTATCTGTTTTGAATTTAAAATTAGAAAAAATTCAACATGAAACAATTTTACAA
CTTGGTGAACGGAACATATGTTATTTTATTAAGACAAGGCCAACTGCAGAACCGTACCCA
CGTCGGTTTAATCAAATAAAAAAATTTCCAATTGGATAA

>protein sequence
MIKLIKTALPALQITPEQEKQLQVYYQYLIEQNQIMNLTTIIKEEEVYLKHFLDSGLLLK
EFSFSKEMTVSDVGSGAGFPGLVLKILCPTIKLTIIESLEKRCLFLQRLVLKLQLKDVEI
IHARAEEYSWAHSESFDIVVSRAVANLGMLLELVVRMVKTSGMIICYKGPNVNAELQAAQ
KTLSVLNLKLEKIQHETILQLGERNICYFIKTRPTAEPYPRRFNQIKKFPIG