SPM_004770

Uniprot: A0A037UN35
Description: peptidyl-tRNA hydrolase
EC number: 3.1.1.29
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA. {ECO:0000256|HAMAP-Rule:MF_00083}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. {ECO:0000256|HAMAP-Rule:MF_00083}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): pth
Gene names (synonym):
Mass: 21,606
Subunit structure [CC]: SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00083}.
Gene ontology (GO): cytoplasm [GO:0005737]; aminoacyl-tRNA hydrolase activity [GO:0004045]; translation [GO:0006412]
Gene ontology IDs: GO:0004045; GO:0005737; GO:0006412
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the PTH family. {ECO:0000256|HAMAP-Rule:MF_00083}.
Protein families: PTH family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92053
UniPathway:
CDD:
Gene3D: cd00462
HAMAP: 3.40.50.1470
InterPro: MF_00083
PANTHER: IPR001328;IPR018171
PIRSF: PTHR17224
PRINTS:
PROSITE:
Pfam: PS01196
ProDom: PF01195
SMART:
SUPFAM:
TIGRFAMs: SSF53178

23862-24432(+)

>nucleotide sequence
ATGAAGTTAATTGTGGGTTTGGGGAATCCAGGCAATGAATATACTTATACAAGACATAAT
ATTGGTTTTTTAGCAATTGCTAAGTTGGTAGATAAATTTGATTTAGCAAAGCCAAAAAAT
GCTTTTAATGCTTTAATATGAGAAACAACAATTAACAACGAGAAAGTTCTTTTTTGCCAA
CCACAGACATTTATGAATTTAAGTGGCACTGCCGTTTATCAAATTAAACAATTTTATAAA
TTAACATGAGAAGATATTATTGTTATTTATGATGATAAAGATATTCCTTTTAATGTTATT
AAGTTAAAAAAGAATGGTTCAAGTGCTGGCCATAATGGGATTAAAGATTTAATTCAAAAA
TTAGGTAGTGAAAATTTTTTAAGGATTCGTCTAGGAATTGGCAAAGATGTCCAGATTCCA
ACCCGAAACTGAGTACTAGGAAAGTTTTCTCCTGCTCAGTTAGAAATTATTAATAATGAT
TTATTAGAAAGAGTTTATCAAATTATGGTGCAATATTTAGTAAAAGCAACTAGTTTTGAT
AAATTGATGAGTCTTTATAATGGCAAATAA

>protein sequence
MKLIVGLGNPGNEYTYTRHNIGFLAIAKLVDKFDLAKPKNAFNALIWETTINNEKVLFCQ
PQTFMNLSGTAVYQIKQFYKLTWEDIIVIYDDKDIPFNVIKLKKNGSSAGHNGIKDLIQK
LGSENFLRIRLGIGKDVQIPTRNWVLGKFSPAQLEIINNDLLERVYQIMVQYLVKATSFD
KLMSLYNGK