SPM_004835

Uniprot: A0A037UN73
Description: glucose-6-phosphate isomerase
EC number: 5.3.1.9
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-phosphate. {ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00500531}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway: PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. {ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00500567}.
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 47,353
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; glucose-6-phosphate isomerase activity [GO:0004347]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]
Gene ontology IDs: GO:0004347; GO:0005737; GO:0006094; GO:0006096
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612, ECO:0000256|SAAS:SAAS00546812}.
Protein families: GPI family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92066
UniPathway:
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR001672;IPR018189
PIRSF: PTHR11469
PRINTS:
PROSITE: PR00662
Pfam: PS00765;PS00174;PS51463
ProDom: PF00342
SMART:
SUPFAM:
TIGRFAMs:

39508-40783(+)

>nucleotide sequence
ATGATTAAAGTAGATTTTACTAATGCATTAGCCGAATCTGTTTTTAACAAATATTTAGGG
CGAGTTAAAGATATTCACCAAATGATTCATAATAAGACAGGATTAGGAAATGATTTCCTT
GGTTGAGTTGAATGACCAAATAATTATGATCAAGCAGAGCTTGCAAAGATGAAACAAACA
GCAAAGCAATTAGCTAGTGAAATTGATGTTTTATTAGTAATTGGAATTGGTGGGAGTTAT
CTTGGCGCACGAGCAGCAATTGAAATGATTAATGGGTTATATAGTCAACAAAAAGTAGAA
ATCATTTATATTGGAAATACAATGTCTTCAACTTATACAGCACAAGTTTTAAAATATCTT
CAAGACAAAAAATTTGGGATTTGTGTTGTGTCTAAATCAGGAACAACAACTGAACCAGCA
ATTGCATTTCGTCTTTGTAAAGAGCTTTTAGAAAAAAAAGAAGGAAATCTAAAAGCAGCT
AACTTAATTGTTGCCATTACAGATAAGCAGAAAGGAGCCCTAAAAACATTAGCTGATAAA
GCAGGATATCAAACCTTTGTTATTCCAGATGACATTGGTGGAAGATATTCAGTGTTAACG
CCAGTTGGTGTTTTTGCAATGCTAGTAAGTGGTATTAACATTGATAATGTTTTTAAAGGA
GCACAACAAGCTTATCAAGACACTTTAATTGATGATTTCACTAATCATGCCTATAAATAT
GCTGTTGGACGTTATATTTTAAATCAAGAGGAAAAATATAAAGCAGAAATGCTTGTAACT
TATGAGTTACAAATGCAGATGATTACCGAATGATGAAAACAATTATTTGGGGAATCAGAA
GGAAAAAATTCAAAGGGTTTACTACCGTTATCATGTGTTTTTTCAACAGATTTACATTCT
CTTGGCCAATTCATTCAAGAAGGGACAAAAAATATTTTATTTGAAACAGTTATTGCAGTT
AAAAAACCACAAATTGATCTTAAACTGTCAAAAGCAGAAGTAGATACTGATGGTTTAAAT
TATCTCGCTGGGAAAACATTACATGAAGTAAATACCATTGCTGTTCAAGGTGTTGTTGCT
GCGCATAGGAAAGTTGGCCATGTGCCAAATATTGTTTTAGAATTTGCAACAATGGATGAT
AAAATGTTTGGTTATTTATCATATTGATTTATGAAAGCTTGTGCAATGTCAGCTTATTTG
TTAGAGATAAATCCATTTGATCAACCCGGAGTTGAGATTTATAAACAAAATATGTTTAAT
TTATTAGGAAAATAA

>protein sequence
MIKVDFTNALAESVFNKYLGRVKDIHQMIHNKTGLGNDFLGWVEWPNNYDQAELAKMKQT
AKQLASEIDVLLVIGIGGSYLGARAAIEMINGLYSQQKVEIIYIGNTMSSTYTAQVLKYL
QDKKFGICVVSKSGTTTEPAIAFRLCKELLEKKEGNLKAANLIVAITDKQKGALKTLADK
AGYQTFVIPDDIGGRYSVLTPVGVFAMLVSGINIDNVFKGAQQAYQDTLIDDFTNHAYKY
AVGRYILNQEEKYKAEMLVTYELQMQMITEWWKQLFGESEGKNSKGLLPLSCVFSTDLHS
LGQFIQEGTKNILFETVIAVKKPQIDLKLSKAEVDTDGLNYLAGKTLHEVNTIAVQGVVA
AHRKVGHVPNIVLEFATMDDKMFGYLSYWFMKACAMSAYLLEINPFDQPGVEIYKQNMFN
LLGK