SPM_004940

Uniprot: A0A037UQS7
Description: 50S ribosomal protein L2
EC number:
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. {ECO:0000256|HAMAP-Rule:MF_01320}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary): rplB
Gene names (synonym):
Mass: 30,814
Subunit structure [CC]: SUBUNIT: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. {ECO:0000256|HAMAP-Rule:MF_01320}.
Gene ontology (GO): large ribosomal subunit [GO:0015934]; rRNA binding [GO:0019843]; structural constituent of ribosome [GO:0003735]; transferase activity [GO:0016740]; translation [GO:0006412]
Gene ontology IDs: GO:0003735; GO:0006412; GO:0015934; GO:0016740; GO:0019843
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the ribosomal protein L2P family. {ECO:0000256|HAMAP-Rule:MF_01320}.
Protein families: Ribosomal protein L2P family
Coiled coil:
Domain [FT]: DOMAIN 124 255 Ribosomal_L2_C. {ECO:0000259|SMART:SM01382}.
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92085
UniPathway:
CDD:
Gene3D:
HAMAP: 2.30.30.30;2.40.50.140;4.10.950.10
InterPro: MF_01320_B
PANTHER: IPR012340;IPR022666;IPR014722;IPR002171;IPR005880;IPR022669;IPR022671;IPR014726;IPR008991
PIRSF: PTHR13691
PRINTS: PIRSF002158
PROSITE:
Pfam: PS00467
ProDom: PF00181;PF03947
SMART:
SUPFAM: SM01383;SM01382
TIGRFAMs: SSF50104;SSF50249

59145-59982(+)

>nucleotide sequence
ATGCCAATTAAGAGTTTTAAACCAGTCACACCGAGTCGTCGTAATATGACGTCATTAGAT
TATTCCGTGCTGACAACTGACCGCCCGGAAAAATCATTAGTTGAAACTCGGAAAAAACAT
GCTGGTCGTAATAACCAAGGAGTTATTACAACAAGACATAAAGGTGGCGGCCACAAAGTT
AAATATCGTATTATTGACTTTAAACGTAATAAGGATAATATTGTTGGAAAAATTGCAACA
ATTGAATATGATCCAAATCGTAATGCCTTTATTTGTTTAGTTAATTATGTTGATGGTGAA
AAAAGATATATTTTGGCACCAAAAACCATTAAAATTGGAATGCAAATTGTTAGTGGTGAG
AAGACGGATATTAAAGTTGGAAACTGCATGAAATTAAAAAACATTCCAGAAGGGACTGTT
CTACATAATTTAGAATTACGTCCAGGCAAAGGTGGACAATTAGCTCGTTCAGCAGGTTCA
TCAGTGCAATTATTAGGGAAAGATGAAGATGGCAAATATGTCACAATTCGGTTAACATCA
GGTGAAGTTCGTAAGGTTTTAGGAGAATGTCGAGCAACAGTTGGTGAAGTTGGAAACGAA
GATTATGCCCTAGTAAATTGAGGAAAAGCGGGACGAAACCGTTGACGTGGAATTCGTCCA
ACTGTTCGTGGGTCAGTTATGAACCCAAATGACCACCCGCATGGTGGGGGAGAAGGTAAA
GCTCCAGTTGGGCGAAAAGCACCAATGACACCATGAGGTAAAAAAGCATTAGGGGTCAAA
ACTCGTAACAAGAAAAAAGCTTCAACTAAATTAATCGTTAGAAGACGTACTAAATAA

>protein sequence
MPIKSFKPVTPSRRNMTSLDYSVLTTDRPEKSLVETRKKHAGRNNQGVITTRHKGGGHKV
KYRIIDFKRNKDNIVGKIATIEYDPNRNAFICLVNYVDGEKRYILAPKTIKIGMQIVSGE
KTDIKVGNCMKLKNIPEGTVLHNLELRPGKGGQLARSAGSSVQLLGKDEDGKYVTIRLTS
GEVRKVLGECRATVGEVGNEDYALVNWGKAGRNRWRGIRPTVRGSVMNPNDHPHGGGEGK
APVGRKAPMTPWGKKALGVKTRNKKKASTKLIVRRRTK