SPM_005080

Uniprot: A0A037UNA0
Description: ATP-dependent DNA helicase
EC number: 3.6.4.12
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. {ECO:0000256|SAAS:SAAS00553768}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 84,322
Subunit structure [CC]:
Gene ontology (GO): ATP binding [GO:0005524]; ATP-dependent DNA helicase activity [GO:0004003]; DNA binding [GO:0003677]
Gene ontology IDs: GO:0003677; GO:0004003; GO:0005524
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the helicase family. UvrD subfamily. {ECO:0000256|SAAS:SAAS00597767}.; SIMILARITY: Contains uvrD-like helicase ATP-binding domain. {ECO:0000256|SAAS:SAAS00553567}.
Protein families: Helicase family, UvrD subfamily
Coiled coil:
Domain [FT]: DOMAIN 7 285 UvrD-like helicase ATP-binding. {ECO:0000259|PROSITE:PS51198}.; DOMAIN 286 559 UvrD-like helicase C-terminal. {ECO:0000259|PROSITE:PS51217}.
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92113
UniPathway:
CDD:
Gene3D:
HAMAP: 1.10.10.160;3.40.50.300
InterPro:
PANTHER: IPR013986;IPR014017;IPR000212;IPR027417;IPR014016
PIRSF: PTHR11070
PRINTS:
PROSITE:
Pfam: PS51198;PS51217
ProDom: PF00580;PF13361
SMART:
SUPFAM:
TIGRFAMs: SSF52540

75178-77371(+)

>nucleotide sequence
ATGCTCAATGAATTTATTGAAAATTTAAATCCAAATCAACGCGAAGCTGTTTTAGCAATT
ACTGGACCAGTGCGAATTATTGCTGGCGCTGGAAGTGGCAAAACACGTATTATTACTAAT
AAAATTGCATATTTAATTAAATATGCTAATTTGCAACCATGACGGATTTGTGCTGTTACG
TTTACTAATAAAGCTACTAATGAAATGAAAACACGTATTGTTGATATGATTGGAAATAGT
GGTCAGCGTTGTCTGATTGCAACTTATCACGCTCTATGTGTTCGTATTTTACGAGAAGAT
ATTATTCATTTAAATTATGATCGGCAATTTAATATTATTGATATGGCAGATCAAGATAGC
ATCATCCGCAATATTTATAAAACATTACCTGTGAAATATGATGCACAAGAAGCAAAAATG
GTCAAGAATTTTATTTCCAAATGAAAAAATGACTTTATTAGTCCAAATAGTGCAAAACAA
TTGGCAAGTGGGGATGAAGTACGATGAGCAGAAATTTATGACGTTTATGAAAAACGTTTA
CGAGAGATAAATAGCGTTGATTTTAATGATTTAATTTTATTAACATATAAGTTATTTAAA
AATAATGTGGAAGTATTGAAAAAATGACAAAATCGTTTTGATTATTTTTTAGTTGATGAA
TTTCAAGATACTAATGAATTACAATTTGATATTATTAAATGATTAGTTGGTGACAATCAC
AATATTACCGTTGTTGGTGACCCTGACCAAACCATTTATTCGTGGCGAGGAGCAAAAATT
AATTTAATTTTAAATTTTGATAAGTATTTTCCACACACCCAAACAATTATTTTAAATGAA
AATTATCGGTCAACACAAAATATTTTATCATTAGCTAATAATTTAATTATTCATAATAAA
AATCGAATTGAAAAAGATTTATTTACTATTAAAGCTTCAGGTCAATTACCAATTTTATAT
CACGGTGCTAATAGTAGCGATGAAAGTGATTTTGTAGCTCATAAAATTAAAACTTTAATG
AAAGAAGAAAATTATAATTATAATGATATTTTAATTTTATATCGTGCCAATTACTTATCG
CGTGATTTAGAAGGAGCTCTTGCTGATTATGGCCTTTCATATCGTATTTTTGGTGCTTTT
AAATTCTATGAACGAAAAGAAATTAAAGATGCCCTTGCTTTTTTAAAAATAATTATGAAT
AATGATCCTTTAGCCATTGAACGGATTTTGTTGTTAACGCCAAAAATTGGACCAAAAGCA
TTTGAACAAATTATGCAAATATTAAAAGAACAGCAAATAATGTTTACAACATTATTGGAA
CAACATTTTGATTTGTTACCATTAAATCTTCAACATAGTTTAAATAAACTGCGAGAAGCA
ATTGTAATAGCATTGGGACAATTACCAACCGCTAAGTCAATTGAAAGCCTATTAGTGCTA
CTATTAGATAAAACAGGTTATTTGCAGCGCTTACGTGATAACTTTGAAGAAGAACGAGAA
GAAAATATTTTAGAATTAATTGCTTCAGTTGTTAAATTTGATAAGCAAAATAAGGATTTA
GAAGGAACGGAATTATTAAGTGAATATTTACAATTGATTTCATTACAAACTGACAGTGAT
AGTGATGATTTAACTGATAATACTATTTCTTTAATGACAATTCATAATGCAAAGGGATTA
GAAAAAAAGGTTGTTTTTATTGTTGGTTTAAATGAAGGAATCTTTCCAACAACGCAGGCT
ATTAAAATGGGAACTGAACAATTAGAAGAAGAACGACGAGCCTTATACGTTGCCATTACA
AGGGCAAAAGAATTGTTGTTTATAAGTTATGCTGATGGTTATTCATATATTACGGGTAAT
GAACGCTTTGAATCACGATTTATTAAAGAATTAAATGGTGATTTTTATGAAAAAGTTAAT
AGTGAAAGGTTGTTTAGTAAGCCAAAGTCAATTACTATTTCTTTTCATAATCAAAGTGAA
AAACAATCACGCACTACTTTTCATCTTAATAAAAACCTTGAGTCATCTTTTAAATCTAAT
CCATGAAAAGTAAATGATACTGTTAGTCATGAATTATTTGGAATTGGAGTTGTTGTTAAA
ATCATTGCCCAAAATGTACAAATTGCTTTTCCGAGTCCTTATAATATCAAAATTATTTCA
GCAGATAGTCAAGCAATTAAAAAAGTAGAATAA

>protein sequence
MLNEFIENLNPNQREAVLAITGPVRIIAGAGSGKTRIITNKIAYLIKYANLQPWRICAVT
FTNKATNEMKTRIVDMIGNSGQRCLIATYHALCVRILREDIIHLNYDRQFNIIDMADQDS
IIRNIYKTLPVKYDAQEAKMVKNFISKWKNDFISPNSAKQLASGDEVRWAEIYDVYEKRL
REINSVDFNDLILLTYKLFKNNVEVLKKWQNRFDYFLVDEFQDTNELQFDIIKWLVGDNH
NITVVGDPDQTIYSWRGAKINLILNFDKYFPHTQTIILNENYRSTQNILSLANNLIIHNK
NRIEKDLFTIKASGQLPILYHGANSSDESDFVAHKIKTLMKEENYNYNDILILYRANYLS
RDLEGALADYGLSYRIFGAFKFYERKEIKDALAFLKIIMNNDPLAIERILLLTPKIGPKA
FEQIMQILKEQQIMFTTLLEQHFDLLPLNLQHSLNKLREAIVIALGQLPTAKSIESLLVL
LLDKTGYLQRLRDNFEEEREENILELIASVVKFDKQNKDLEGTELLSEYLQLISLQTDSD
SDDLTDNTISLMTIHNAKGLEKKVVFIVGLNEGIFPTTQAIKMGTEQLEEERRALYVAIT
RAKELLFISYADGYSYITGNERFESRFIKELNGDFYEKVNSERLFSKPKSITISFHNQSE
KQSRTTFHLNKNLESSFKSNPWKVNDTVSHELFGIGVVVKIIAQNVQIAFPSPYNIKIIS
ADSQAIKKVE