SPM_005335

Uniprot: A0A037UR10
Description: cytidylate kinase
EC number: 2.7.4.25
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + (d)CMP = ADP + (d)CDP. {ECO:0000256|HAMAP-Rule:MF_00238, ECO:0000256|SAAS:SAAS00321177}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 10 18 ATP. {ECO:0000256|HAMAP-Rule:MF_00238}.
Site:
Gene names (primary): cmk
Gene names (synonym):
Mass: 25,030
Subunit structure [CC]:
Gene ontology (GO): cytoplasm [GO:0005737]; ATP binding [GO:0005524]; cytidylate kinase activity [GO:0004127]; pyrimidine nucleotide metabolic process [GO:0006220]
Gene ontology IDs: GO:0004127; GO:0005524; GO:0005737; GO:0006220
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the cytidylate kinase family. Type 1 subfamily. {ECO:0000256|HAMAP-Rule:MF_00238, ECO:0000256|SAAS:SAAS00558193}.
Protein families: Cytidylate kinase family, Type 1 subfamily
Coiled coil:
Domain [FT]: DOMAIN 6 215 Cytidylate_kin. {ECO:0000259|Pfam:PF02224}.
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92160
UniPathway:
CDD:
Gene3D:
HAMAP: 3.40.50.300
InterPro: MF_00238
PANTHER: IPR003136;IPR011994;IPR027417
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF02224
SMART:
SUPFAM:
TIGRFAMs: SSF52540

130574-131246(+)

>nucleotide sequence
ATGATGAAAATAAATATTGCGATTGATGGCCCGGCTGGTAGTGGAAAATCTTCTGCTGGT
TATGAATTGGCCAAAAAACTAAATTATCAGTTTATTGATACTGGTCTAACTTATCGTGCT
TTTACTTATTTTTGTGTAAAAGTTGGAGTTGATTTTACAAATCATCATCAGTTGCAAGCA
CAATTAGCAAACTTTAAATATCAAGTAATTAATAACCATGTTTATGTTAATAATGAAGAT
ATTACTGATAAGTTGCAAACTAATCTTGTTCTTGATAATATTAACAAAATTACTGGACTT
GATTTTATTCGAGCATCAATGGTTTGTTTACAACGAAAATTAGTGGTTAAAAAAGGTAAT
GTTGTTGTTGGACGAGACATTACTACTGTTGTTCTCCCTGATGCGGAAGTGAAAATTTAC
TTAACAGCTAGTATTACAGCACGAGCTAACCGCCGATGAAATCAAAATCAAGAAAACAAT
ATTGTTCCAAATAATTTAGCAGAAATTAAAGTCAAATTAAAAGAACGAGATTATGTTGAT
ACAACACGAGCGGTAGGACCATTAAAAATTGCTCCTGATGCGGTTGTTGTGGATAGTAGT
AAGTTAACATTTGAACAAACAGTAACTAAGATTTATCAAGTAGTATGTAATTATAAGAAA
GCAGGAAAATAA

>protein sequence
MMKINIAIDGPAGSGKSSAGYELAKKLNYQFIDTGLTYRAFTYFCVKVGVDFTNHHQLQA
QLANFKYQVINNHVYVNNEDITDKLQTNLVLDNINKITGLDFIRASMVCLQRKLVVKKGN
VVVGRDITTVVLPDAEVKIYLTASITARANRRWNQNQENNIVPNNLAEIKVKLKERDYVD
TTRAVGPLKIAPDAVVVDSSKLTFEQTVTKIYQVVCNYKKAGK