SPM_005610

Uniprot: A0A037UL50
Description: phosphatidate cytidylyltransferase
EC number: 2.7.7.41
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: CTP + phosphatidate = diphosphate + CDP-diacylglycerol. {ECO:0000256|RuleBase:RU003938}.
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway: PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3. {ECO:0000256|RuleBase:RU003938}.
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 41,515
Subunit structure [CC]:
Gene ontology (GO): integral component of membrane [GO:0016021]; phosphatidate cytidylyltransferase activity [GO:0004605]; CDP-diacylglycerol biosynthetic process [GO:0016024]
Gene ontology IDs: GO:0004605; GO:0016021; GO:0016024
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the CDS family. {ECO:0000256|RuleBase:RU003938}.
Protein families: CDS family
Coiled coil:
Domain [FT]:
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92207
UniPathway:
CDD:
Gene3D:
HAMAP:
InterPro:
PANTHER: IPR000374
PIRSF:
PRINTS:
PROSITE:
Pfam: PS01315
ProDom:
SMART:
SUPFAM:
TIGRFAMs:

181293-182382(+)

>nucleotide sequence
ATGAACAATCAGGAAGATAATGTTCTTGTGAATGAAAATGAAACATCGACAGAAGAGCAC
AATTTAACAAATAACGTATCAAAAAATAAGGAACATAAAGGAATGTTTCAAAAAAAATAT
GTTGCTCGTCATATTACATTTTATTCGTTATTAGTTTTTTTAAGTTTATATTTATTCACA
GGAGCAATCGCAACAGAATGGCATAATAATGTTCCACATATTGAAATTGCTAATTATGTT
TTTATTGGAATTAATGCTGTTATTTTAGGCTTAGTTAACTATGAAATTTTGCGATTAGTT
GGGGGAACAAAGTGACCAATTTATACGCAAATTATTACATATTTATTGATAATTTTTTTA
TTTTTGTTTCCAGTTGAATCAATCGCAAATGAATATGGTGGAATTGGAGCAATTAATTAT
CCGTTTTATACGTTATTAAATTGAAATTGATTAAAACCTTGAATTATCTTTGTTATTTAT
TTATGTGCTATTTTTGGATATTATTGTTTAGTATTTAGTTCAAAAGAAATTACTTTTGGT
AAAATGACATTAGTTTTAATTTTTACCTTATATTTAACTTTTGCTTTAAAAGCAATGAAT
AAATTTATGTTAAATCCTGCCTATGGTTGAAGTAGCGTGGTTTGATTAGCATTAATTATT
ATTTTAACTGATACTTTTGCTTTTGTTGGAGGTGTTACTTATGGAAAGCATAAATTAGCG
CCAACAATATCTCCAAACAAAACATGAGAAGGAGCTGTGACAGGAACAATCTTAGCAGCA
GGAATTGCAATTACTTATGCAATTTTAATGTTTCATTTTGCAACTAGTAACCATTGGGTT
TTTAACTTTTTCTCAAATGATAATGATAAAAATGTCATGCGTTATGTAATTTATATTTTA
TTAGCATTTGTATTAAGTATTTTATCACAATTGGGTGATTTATCATTTTCTTGAATTAAA
CGTCGTTATAATATTAAAGATTTTAGCAATTTATTACCTGGGCATGGTGGTGTTTTAGAT
CGTTTGGATTCATTTTCATTAGTCTTTTTTGTAATGTTTATCATTTCCAATATAGTATTA
CAACGATAA

>protein sequence
MNNQEDNVLVNENETSTEEHNLTNNVSKNKEHKGMFQKKYVARHITFYSLLVFLSLYLFT
GAIATEWHNNVPHIEIANYVFIGINAVILGLVNYEILRLVGGTKWPIYTQIITYLLIIFL
FLFPVESIANEYGGIGAINYPFYTLLNWNWLKPWIIFVIYLCAIFGYYCLVFSSKEITFG
KMTLVLIFTLYLTFALKAMNKFMLNPAYGWSSVVWLALIIILTDTFAFVGGVTYGKHKLA
PTISPNKTWEGAVTGTILAAGIAITYAILMFHFATSNHWVFNFFSNDNDKNVMRYVIYIL
LAFVLSILSQLGDLSFSWIKRRYNIKDFSNLLPGHGGVLDRLDSFSLVFFVMFIISNIVL
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