SPM_005845

Uniprot: A0A037UNS9
Description: pseudouridine synthase
EC number: 5.4.99.-
Annotation score: 1 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity:
Cofactor:
Enzyme regulation:
Function [CC]:
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding:
Site:
Gene names (primary):
Gene names (synonym):
Mass: 28,115
Subunit structure [CC]:
Gene ontology (GO): pseudouridine synthase activity [GO:0009982]; RNA binding [GO:0003723]; pseudouridine synthesis [GO:0001522]
Gene ontology IDs: GO:0001522; GO:0003723; GO:0009982
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the pseudouridine synthase RsuA family. {ECO:0000256|RuleBase:RU003887, ECO:0000256|SAAS:SAAS00545889}.; SIMILARITY: Contains S4 RNA-binding domain. {ECO:0000256|SAAS:SAAS00568442}.
Protein families: Pseudouridine synthase RsuA family
Coiled coil:
Domain [FT]: DOMAIN 2 70 S4 RNA-binding. {ECO:0000259|PROSITE:PS50889}.
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92248
UniPathway:
CDD:
Gene3D:
HAMAP: 3.10.290.10
InterPro:
PANTHER: IPR020103;IPR000748;IPR018496;IPR006145;IPR002942
PIRSF:
PRINTS:
PROSITE:
Pfam: PS01149;PS50889
ProDom: PF00849;PF01479
SMART:
SUPFAM: SM00363
TIGRFAMs: SSF55120

231572-232316(+)

>nucleotide sequence
ATGGAACGCTTACAAAAAGTTATTGCAGCAAAAGGTTATTGCTCACGACGAAAAGCAGAA
GAACTAATTATTCAAGGACGAGTTAAAGTTAATAATGTTGTGGTAACAACATTGGGTACT
AAAGTTGGCAAAAATGATCAAATACAAGTAAATAATCAAATTCTTATGAATGAAAATTCA
AATAAGGTTTATTTAATGCTGAACAAACCACGAAATTGTGTTTCAACGATGTATGATCCG
CAACATCGCAAAACAGTTTTAACTTATGTTAAAGGTATTTCAGAACGAATTTATCCGGTA
GGTCGCTTAGACTATGATACTAGTGGTCTTTTACTATTGACTAATGATGGAGAATTTACT
AATATTATTACACACCCAAGTCATATTATTAATAAGACATATCATGTTTTAGTTTCTGGT
TATCTTTCAAAACAACAATTACAACAATTAGCAACAGGAATTGAAATTGAGCCAGGAATT
ATAACAAGCCAAGCACAAGCAAAATTAGTAAAATATGAAGAAGCAAAAAATGTTTCGATT
CTTTTATTAACTATTCATGAAGGCAGAAAACATCAAGTTAAAAAAATGATACAAGCATTA
GGGCATGAAGTTATTAAATTAAAACGAATTGCAATTGGTTTTTTACAATTAGATGAAACA
TTAAAGCCTGGTGAATGACGTTATTTAAAGCCCAAAGAAATTAAACTTTTTTTTGGAATA
GCATCACACTTAAAAACAAAATAA

>protein sequence
MERLQKVIAAKGYCSRRKAEELIIQGRVKVNNVVVTTLGTKVGKNDQIQVNNQILMNENS
NKVYLMLNKPRNCVSTMYDPQHRKTVLTYVKGISERIYPVGRLDYDTSGLLLLTNDGEFT
NIITHPSHIINKTYHVLVSGYLSKQQLQQLATGIEIEPGIITSQAQAKLVKYEEAKNVSI
LLLTIHEGRKHQVKKMIQALGHEVIKLKRIAIGFLQLDETLKPGEWRYLKPKEIKLFFGI
ASHLKTK