SPM_006185

Uniprot: A0A037ULH2
Description: exodeoxyribonuclease V subunit alpha
EC number: 3.6.4.12
Annotation score: 2 out of 5
Miscellaneous [CC]:
Protein existence: Inferred from homology
Catalytic activity: CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. {ECO:0000256|HAMAP-Rule:MF_01488}.
Cofactor:
Enzyme regulation:
Function [CC]: FUNCTION: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. {ECO:0000256|HAMAP-Rule:MF_01488}.
Pathway:
Active site:
Binding site:
Calcium binding:
DNA binding:
Metal binding:
Nucleotide binding: NP_BIND 343 347 ATP. {ECO:0000256|HAMAP-Rule:MF_01488}.
Site:
Gene names (primary): recD2
Gene names (synonym):
Mass: 82,724
Subunit structure [CC]:
Gene ontology (GO): ATP binding [GO:0005524]; ATP-dependent 5'-3' DNA helicase activity [GO:0043141]; DNA binding [GO:0003677]
Gene ontology IDs: GO:0003677; GO:0005524; GO:0043141
Chain:
Signal peptide:
Domain [CC]:
Sequence similarities: SIMILARITY: Belongs to the RecD family. RecD-like subfamily. {ECO:0000256|HAMAP-Rule:MF_01488}.
Protein families: RecD family, RecD-like subfamily
Coiled coil:
Domain [FT]: DOMAIN 332 474 AAA. {ECO:0000259|SMART:SM00382}.
Motif:
Region:
EMBL: AGBZ02000004
ProteinModelPortal:
MEROPS:
EnsemblBacteria KO: KAI92297
UniPathway:
CDD:
Gene3D:
HAMAP: 3.40.50.300
InterPro: MF_01488
PANTHER: IPR003593;IPR006345;IPR027417;IPR029493;IPR027785
PIRSF:
PRINTS:
PROSITE:
Pfam:
ProDom: PF14490;PF13538
SMART:
SUPFAM: SM00382
TIGRFAMs: SSF52540

298708-300871(+)

>nucleotide sequence
ATGGCTGAAAAAATACGGGGTTATTTAAAATTAATTGTTTTTGAATCTAATAATGGTTAT
CGGATTTGTAAATTTCAATTAGAAAATGATAAAACACATTTTATTTTTATTAAAGGATTT
TTATCAGCTTTACAACCAGAACAATTATATGAATTATGTGGGGAATTTGTATATAATGAA
CGTTATGGTGAAAATTTTGAAGTTAAAGAAATTCATAAACTTGCTCCGCGTAGTAATGAT
GAGGTCTTAAAATATTTAACTAGTAGTTTATTTCCAACAATTGGTGAAAAAGCAGCACAA
ATAATTATTGATTATTATCAAACAGATGTGATTACTAAAATTAAAGAAAATTTATCAACC
TTACATCAAATCCCAGGGATTAGTGTTAAACAAGCTAATATTATTGCAAAAGTATTTCAG
TCAATGAGTCGTGATGATGAATTAAATCATCAATTTAATCAAAAAGGATTATCGCTACAA
GTTTTATCTTTATTAAAAACAAAATATAATGTTGACCAGATTTATGCTTTATTAAAAAAA
GATCCTTATTCATTGTTATTAAAAGATAATATTGCTTTTAAAACAATTGATAAGATTTAT
TTAGCATTTGAGCAAGAACCTTTTAGTAATATTCGAATTGGTTATTATGCCTGATATTTA
GCAAAGGAATTTTGTAATAATAATGGTGATACTTATTTAACATTAAATGAATTAACAAAA
ATTTTACAAAAGCATTTTTCTTCTTTAACAAAAGAACAATTATTAGCAGGATTAAAATAT
AGTAAAGAAATTAAATTACTAATTTTTAAGAATGATAAAATTTATGTTGCAGAAGTATAT
CATAGTGAAATAAATATTGCTGCAATGTTAGTTGGCTTGAACACAACTGACCAATATGAT
GATCAAAAATTAACAGAAGAATTAGAGAAGTTAACAAATAAAAAACAAATTATTTATAAT
ATGAATCAAACAAAAGCAATTAAGGCTGCCGTGCATTCTAATTTTTTAGTTATTATTGGG
GGACCTGGAACGGGAAAAACAACAGTTGTTGATGGCATTGTTAGTCTTTTAAAAAAAGTT
TACCAACAATCAAAAATTGTGTTAGCAGCACCAACAGGAAAAGCAGCAAAACGATTACGA
GAAAAAACTGGTCAGAAAGCTTTAACAATTCATAAATTATTAAAATATGATGCTTTAACT
AATCAGTTTTTTTATAACGAAAATAATCCTTTAGAAAATGATATTTTAATTTTAGATGAA
GTTAGTATGGTTGATAGTTTGTTATTAGCACAAATTGCCAAAGCTAGTGTTAATTTGCGT
AAATTAATTTTAATTGGTGATCCAAATCAATTGCCATCAGTTGCTTGTGGTGATTTGTTA
CGAGATATTATTCAAAGTGATGTTTTTAATGTTATTAAATTAGAAGAAGTTTATCGGCAA
GAAGCTGGAAATGACATTTTAGAACTATCTTATGCAATTGAACAAGAACATTTTGAAGAT
AATAATTTATTTGATAAAAAAGATTTTACTTTTATTAATGAAACTGATTCGCAAGCATTA
TTAACAGCTGTTGGTGATTTATATCAAAACATTAGCAATCAATATGAAGCAGATTATAAT
GCTATCCAAGTAATTGCTCCAATGTATAATGGTCCAGTTGGAATTAATGCATTAAATACT
TATTTACAAAATCGAATGAATCATGCAGTTGGCCAAAAAGAAATTAAGATTGGACATCGT
TTTTTTCGAGTTAATGATAAAGTTATGCAACTTAAAAATCGACCTGAATTAGAAATTTAT
AATGGTGATGTTGGCATTATTATTGATATTAAAAAAGATAAAAATTTAAATGATGTTATT
TTAGTAAAATATGATAATGTTATTACATATACTAAAGAACTTTATTATGATATTACTTTA
GCTTATGCTTGTAGTGTTCATAAGTTACAGGGCAGTGAATATGATAATATTATTTTTGTA
ATAACAAAAAGTTTTTGAATGATGTTAAAACGAAATCTAATTTATACAGCAATTACCCGT
GCTAAAACTAAGTTGTATTTAATTGGTGAACCATCAGCATTTTTATATGGAGTTAATAAT
TTACCACAAAAGCGTCGAACAACTTTACAAGAAAAAATTAAAACATTTTTAAAAGAGCAA
TAG

>protein sequence
MAEKIRGYLKLIVFESNNGYRICKFQLENDKTHFIFIKGFLSALQPEQLYELCGEFVYNE
RYGENFEVKEIHKLAPRSNDEVLKYLTSSLFPTIGEKAAQIIIDYYQTDVITKIKENLST
LHQIPGISVKQANIIAKVFQSMSRDDELNHQFNQKGLSLQVLSLLKTKYNVDQIYALLKK
DPYSLLLKDNIAFKTIDKIYLAFEQEPFSNIRIGYYAWYLAKEFCNNNGDTYLTLNELTK
ILQKHFSSLTKEQLLAGLKYSKEIKLLIFKNDKIYVAEVYHSEINIAAMLVGLNTTDQYD
DQKLTEELEKLTNKKQIIYNMNQTKAIKAAVHSNFLVIIGGPGTGKTTVVDGIVSLLKKV
YQQSKIVLAAPTGKAAKRLREKTGQKALTIHKLLKYDALTNQFFYNENNPLENDILILDE
VSMVDSLLLAQIAKASVNLRKLILIGDPNQLPSVACGDLLRDIIQSDVFNVIKLEEVYRQ
EAGNDILELSYAIEQEHFEDNNLFDKKDFTFINETDSQALLTAVGDLYQNISNQYEADYN
AIQVIAPMYNGPVGINALNTYLQNRMNHAVGQKEIKIGHRFFRVNDKVMQLKNRPELEIY
NGDVGIIIDIKKDKNLNDVILVKYDNVITYTKELYYDITLAYACSVHKLQGSEYDNIIFV
ITKSFWMMLKRNLIYTAITRAKTKLYLIGEPSAFLYGVNNLPQKRRTTLQEKIKTFLKEQ